Merck
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E-081

Supelco

依替唑仑标准液 CRM 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
C17H15ClN4S
CAS Number:
Molecular Weight:
342.85
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

质量水平

300

等级

certified reference material

形式

liquid

特点

(Snap-N-Spike®)

包装

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland)

浓度

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

格式

single component solution

储存温度

−20°C

SMILES string

CCC1=CC2=C(S1)N3C(CN=C2C4=CC=CC=C4Cl)=NN=C3C

InChI

1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3

InChI key

VMZUTJCNQWMAGF-UHFFFAOYSA-N

一般描述

经认证的溶液标准,可用于临床毒理学、尿液药物测试或法医分析中的LC/MS或GC/MS苯二氮卓测试方法。依替唑仑,商品名为Etilaam、Etizola或Depas,是一种苯二氮卓类似物,可用于失眠、焦虑或惊恐发作的短期治疗。依替唑仑也被作为化合致幻药销售,在欧洲和美国都有药物滥用的案例。

生化/生理作用

依替唑仑是一种噻吩并二氮杂卓抗焦虑药,与其他苯二氮卓类药物相比具有较低的依赖性。它与其他苯并二氮杂卓类药物的不同之处在于其分子具有噻吩环而不是苯环。它具有抗惊厥、镇静、抗焦虑、遗忘、催眠和肌肉松弛作用。它是通过作用于苯二氮卓受体而发挥作用的。它被用于治疗失眠、中度抑郁和社交焦虑症,并偶尔用于治疗眼睑痉挛和皮肤病变。

法律信息

CERILLIANT is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(F)

49.5 °F

闪点(C)

9.7 °C

Certificate of Analysis

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Certificate of Origin

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