Merck

F-013

Supelco

芬太尼标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C22H28N2O
CAS号:
分子量:
336.47
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

浓度

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

格式

single component solution

储存温度

−20°C

SMILES string

CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3

InChI

1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3

InChI key

PJMPHNIQZUBGLI-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

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F-001A-129I-038
vibrant-m

F-013

芬太尼标准液 溶液

vibrant-m

F-001

芬太尼-D5标准液 CRM 溶液

vibrant-m

A-129

乙酰芬太尼 溶液

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

storage temp.

−20°C

storage temp.

-10 to -25°C

storage temp.

−20°C

storage temp.

−20°C

concentration

1.0 mg/mL in methanol

concentration

100 μg/mL in methanol

concentration

50 μg/mL in methanol

concentration

100 μg/mL in methanol (as a free base)

一般描述

该认证的溶液标准适用于各种 LC/MS 或 GC/MS 测试应用,包括从法医分析、临床毒理学和止痛处方监测到尿液药物测试和药物研究。

芬太尼属于合成阿片类药物,具有强效的μ-阿片受体激动作用。它以麻醉和镇痛特性而闻名,效力是海洛因的 100 倍。芬太尼以 Duragesic®、Actiq®和Fentora® 等各种商品名出售,在镇痛活性方面比吗啡更有效。

应用

该认证标准溶液(CRM)还可作如下用途:
  • 使用基于液相色谱-串联质谱(LC-MS/MS)的程序对头发样品中芬太尼及其衍生物进行多残留分析
  • 采用高效液相色谱与二极管阵列检测和安培检测的组合分别和同时测定街头检获样品中的海洛因、芬太尼及其 10 种类似物
  • 开发超高效液相色谱-串联质谱(UHPLC-MS/MS)技术来估算头发样品中的 31 种芬太尼类似物和 6 种合成阿片类药物
  • 通过液-液萃取后的液相色谱-串联质谱(LC-MS/MS)对芬太尼及其类似物和合成阿片类药物全血样品进行分离和定量分析
  • 通过纸喷雾-质谱法对尿液和镇痛片浆液中的芬太尼和去芬太尼含量进行半定量分析

特点和优势

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书(CoA),包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试,以确保准确性和保质期
  • 使用合格的精密天平进行重量准备,以确保最小不确定性
  • 氩气环境下火焰密封,装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式,以提高实验室效率

法律信息

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup


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吗啡标准液 溶液 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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吗啡标准液 溶液

[Pain therapy. Treating pain patients with opioid preparations].
MMW Fortschritte der Medizin, 155(6), 70-71 (2013-05-25)
Nele Plock et al.
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Intranasal Fentanyl Spray (INFS) was developed for the treatment of breakthrough pain (BTP) in cancer patients using a new route of administration. Dose strengths of 50, 100, and 200 μg INFS (Instanyl®) are currently on the market, however, some adult
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Seven grizzly (Ursus arctos; four male, three female) and three black (Ursus americanus; two male, one female) bears caught in culvert traps or leg snares were immobilized in northwestern Wyoming with carfentanil and xylazine at doses, respectively, of 0.011 ±
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Opioids may cause progressive enhancement of pain sensitivity (opioid-induced hyperalgesia [OIH]) and thus, exacerbate existing pain. Animal studies also demonstrate paradoxical OIH with an ultralow dose (ULD, subanalgesic) of opioid; eg, the μ-opioid, morphine. Repeated administration of ULD-morphine resulted in

商品

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

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