所有图片(1)

H-090

Supelco

1α,25-二羟基维生素D2标准液 溶液

5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
C28H44O3
CAS号:
分子量:
428.65
EC 号:

质量水平

300

等级

certified reference material

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

浓度

5 μg/mL in ethanol

特色行业

Clinical Testing
Clinical Testing
Clinical Testing

格式

single component solution

储存温度

−70°C

SMILES string

CC(\C=C\C(C)C(C)(C)O)C1CCC2C(\CCCC12C)=C\C=C3\CC(O)CC(O)C3=C

InChI

1S/C28H44O3/c1-18(9-10-19(2)27(4,5)31)24-13-14-25-21(8-7-15-28(24,25)6)11-12-22-16-23(29)17-26(30)20(22)3/h9-12,18-19,23-26,29-31H,3,7-8,13-17H2,1-2,4-6H3/b10-9+,21-11+,22-12-

InChI key

ZGLHBRQAEXKACO-WQIUIVEWSA-N

一般描述

准确制备定量引用对于准确评估患者维生素 D 水平非常关键。该认证的加标溶液 ® 适用于研究和临床环境中的关键定量应用,包括:用于制备用于 LC/UV 和 LC-MS/MS 维生素 D 测定的质控品和校准品;作为系统调整/适用性标准;线性验证;内部能力验证;用于 OEM 制备试剂、开发检测试剂盒和仪器 IQ/OQ。稳定、定量的解决方案格式为用户提供了显著的益处,包括节省材料、提高劳动效率和使用方便。保存稳定的Snap-N-Spike®形式可帮助实验室免去痛苦的称重操作,并能在使用前将已知浓度的分析物加入到所选择的基质中。

法律信息

CERILLIANT is a registered trademark of Cerilliant Corporation
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

象形图

FlameExclamation mark

警示用语:

Danger

危险声明

预防措施声明

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK Germany

WGK 1

闪点(F)

57.2 °F - closed cup

闪点(C)

14 °C - closed cup

分析证书

原产地证书 (CofO)

R A Henik et al.
Journal of the American Veterinary Medical Association, 215(11), 1644-1649 (2003-10-22)
Rickets was diagnosed in a 1-year-old cat with a history of weakness, osteopenia, and recurrent fractures. Processes causing rickets include vitamin D deficiency caused by inadequate, nutrition, lack of exposure to sunlight, defective metabolism of parent vitamin D to active...
Richard J Grostern et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 120(5), 607-612 (2002-05-25)
Although calcitriol (1,25-dihydroxycholecalciferol) and vitamin D(2) inhibit retinoblastoma growth in the athymic (nude) mouse xenograft (Y-79 cell line) model of retinoblastoma, they can cause severe toxicity. To examine the toxicity of and dose-dependent response for the inhibition of tumor growth...
Frederick G Strathmann et al.
Clinical chemistry, 57(9), 1279-1285 (2011-07-20)
1α,25-dihydroxy vitamin D [1,25(OH)(2)D] is the active metabolite of vitamin D. Antibody-based detection methods lack specificity, but when combined with isotope dilution/ultra-performance liquid chromatography (UPLC)-tandem mass spectrometry, immunoextraction provides an attractive method for 1,25(OH)(2)D. We developed a method for simultaneous...
Rachael M Biancuzzo et al.
The Journal of clinical endocrinology and metabolism, 98(3), 973-979 (2013-02-07)
The purpose of this study was to determine 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and 1,25-dihydroxyvitamin D2 [1,25(OH)2D2] levels in healthy adults consuming 1000 IU vitamin D2 or vitamin D3 per day for 11 weeks. Blood from 34 healthy male and female adults...
D R Zimmerman et al.
Archives of biochemistry and biophysics, 392(1), 14-22 (2001-07-27)
Calcitroic acid (1 alpha-hydroxy-23 carboxy-24,25,26,27-tetranorvitamin D(3)) is known to be the major water-soluble metabolite produced during the deactivation of 1 alpha,25-dihydroxyvitamin D(3). This deactivation process involves a series of oxidation reactions at C(24) and C(23) leading to side-chain cleavage and...

技术文章

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This application shows an Ascentis Express F5 provided rapid resolution of the isobaric vitamin D metabolites. MS detection provides the necessary secondary resolution.

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The metabolic role and health implications of the various vitamin D isoforms are of current clinical interest. Therefore, it is important to have an analytical method that will resolve all of the known isoforms with necessary sensitivity and specificity

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