Merck
所有图片(1)

H-107

Supelco

1,25-二羟基维生素 D3-13C3 (25,26,27-13C3)标准液 CRM 溶液

5 μg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
13C3C24H44O3
分子量:
419.61
EC 号:
NACRES:
NA.24

质量水平

300

等级

certified reference material

形式

liquid

特点

(Snap-N-Spike®)

包装

ampule of 1 mL

manufacturer/tradename

Cerilliant®

浓度

5 μg/mL in ethanol

mp

-143.99 °C

application(s)

clinical testing
clinical testing

格式

single component solution

储存温度

−70°C

SMILES string

O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@]3([H])[C@H](C)CCC[13C](O)([13CH3])[13CH3])([H])[C@]3(C)CCC\2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i3+1,4+1,26+1

InChI key

GMRQFYUYWCNGIN-SYUIRNBGSA-N

一般描述

一种稳定标记的内部标准,适用于LC-MS/MS测定1,25-二羟基维生素D3水平。1,25-二羟基维生素D3,也称为骨化三醇,是维生素D的激素活性代谢物,负责调节钙。1,25-二羟基维生素D3的测定用于区分原发性甲状旁腺功能亢进和癌症高钙血症,并用于鉴别维生素D依赖型佝偻病。

法律信息

CERILLIANT is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

象形图

FlameExclamation mark

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(F)

57.2 °F - closed cup

闪点(C)

14.0 °C - closed cup

分析证书

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原产地证书 (CofO)

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更多文件

Quotes and Ordering

Mark A Crumling et al.
PloS one, 7(12), e53280-e53280 (2013-01-04)
Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as
Matthew B Pomrenze et al.
Cell reports, 29(1), 13-21 (2019-10-03)
Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behaviors. We dissected the relative roles of GABA, CRF
Fang Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(26), 12986-12995 (2019-06-12)
The aberrant hedgehog (Hh) pathway plays important roles in multiple cancer types, therefore serving as a promising drug target. Current clinically available hedgehog-targeted drugs act mostly by antagonizing the upstream component smoothened; however, both primary and acquired resistance to FDA-approved
Eric Wang et al.
Cancer cell, 35(3), 369-384 (2019-02-26)
RNA-binding proteins (RBPs) are essential modulators of transcription and translation frequently dysregulated in cancer. We systematically interrogated RBP dependencies in human cancers using a comprehensive CRISPR/Cas9 domain-focused screen targeting RNA-binding domains of 490 classical RBPs. This uncovered a network of
Masao Nakagawa et al.
Cancer cell, 34(2), 286-297 (2018-07-31)
Adult T cell leukemia/lymphoma (ATLL) is a frequently incurable disease associated with the human lymphotropic virus type I (HTLV-I). RNAi screening of ATLL lines revealed that their proliferation depends on BATF3 and IRF4, which cooperatively drive ATLL-specific gene expression. HBZ, the

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