Merck
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05-1117

Sigma-Aldrich

Anti-VEGF Antibody, clone VG1

ascites fluid, clone VG1, from mouse

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别名:
Vascular permeability factor, vascular endothelial growth factor, vascular endothelial growth factor A, vascular endothelial growth factor isoform VEGF165
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

ascites fluid

克隆

VG1, monoclonal

种属反应性

mouse, human, rat

技术

western blot: suitable

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

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此商品
AB1876-IABS82MABC595
Anti-VEGF Antibody, clone VG1 ascites fluid, clone VG1, from mouse

05-1117

Anti-VEGF Antibody, clone VG1

Anti-VEGF-A Antibody from rabbit, purified by affinity chromatography

AB1876-I

Anti-VEGF-A Antibody

抗-VEGF抗体 from rabbit, purified by affinity chromatography

ABS82

抗-VEGF抗体

抗-VEGF 165b抗体,克隆56/1 clone 56/1, 1 mg/mL, from mouse

MABC595

抗-VEGF 165b抗体,克隆56/1

species reactivity

mouse, human, rat

species reactivity

rat, mouse

species reactivity

mouse, rat, human

species reactivity

human, mouse, rat

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

mouse

clone

VG1, monoclonal

clone

polyclonal

clone

polyclonal

clone

56/1, monoclonal

technique(s)

western blot: suitable

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

一般描述

VEGF (Vascular endothelial growth factor, VEGFA, VEGF-A), a dimeric ligand, is among the most potent angiogenic mitogens. VEGF is secreted by tumor cells and other cells exposed to hypoxia. VEGF is a highly specific mitogen for vascular endothelial cells. Seven VEGF isoforms (a, b, c, d, e, f, g) are generated as a result of alternative splicing from a single VEGF gene. The most commonly studied isoforms are VEGF121, VEGF165, and VEGF189 (f, d and b, respectively) All seven isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The expression of VEGF is potentiated and is secreted by tumor cells in response to hypoxia, by activated oncogenes, and by a variety of cytokines.

特异性

Detects the 121, 165, and 189 amino acid isoforms of VEGF.

免疫原

Recombinant human VEGF 189aa isoform

应用

Detect VEGF using this Anti-VEGF Antibody, clone VG1 validated for use in WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

质量

Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: A 1:500 dilution of this antibody detected VEGF on 10 µg of NIH/3T3 cell lysate.

目标描述

Approx. 12-28 kDa

联系

Replaces: MAB3734

外形

Unpurified
Unpurified mouse monoclonal IgG1κ in ascites fluid containing no preservatives.

储存及稳定性

Stable for 12 months at -20°C from date of receipt.
Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
NIH/3T3 cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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