Merck
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05-652

Sigma-Aldrich

Anti-MUC1/episialin Antibody, clone 214D4

clone 214D4, Upstate®, from mouse

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别名:
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, Episialin, H23AG, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100

抗体形式

purified antibody

克隆

214D4, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

同位素/亚型

IgG1

NCBI登记号

NM_182741

UniProt登记号

P15941

运输

dry ice

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Anti-MUC1/episialin Antibody, clone 214D4

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Anti-PKC Antibody (α, β, γ), clone M110

Anti-Mps1 Antibody, NT, clone 3-472-1 clone 3-472-1, Upstate®, from mouse

Sigma-Aldrich

05-682

Anti-Mps1 Antibody, NT, clone 3-472-1

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

purified antibody

clone

214D4, monoclonal

clone

23A8, monoclonal

clone

M110, monoclonal

clone

3-472-1, monoclonal

species reactivity

human

species reactivity

rat, human, mouse

species reactivity

rat, human, mouse

species reactivity

human

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

western blot: suitable

特异性

MUC1/episialin

免疫原

Fusion protein, human b-gal-episialin/MUC1 repeat domain

应用

Anti-MUC1/episialin Antibody, clone 214D4 detects level of MUC1/episialin & has been published & validated for use in FC, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

质量

routinely evaluated by immunohistochemistry

目标描述

none given

外形

Protein G Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified

储存及稳定性

2 years at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

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Ilene K Gipson et al.
Cornea, 30(12), 1346-1352 (2011-11-18)
To determine if levels of the glycocalyx membrane mucins, MUC1 and MUC16, and the secreted goblet cell mucin MUC5AC are altered in conjunctival cells and tears of postmenopausal women presenting with a history of non-Sjögren dry eye and if mucin
Neeraja Dharmaraj et al.
Biology of reproduction, 81(6), 1182-1188 (2009-08-18)
Embryo implantation involves direct interaction of the blastocyst with the luminal epithelium of the receptive uterus. MUC1, a transmembrane mucin expressed at the apical surface of uterine epithelia, acts as a barrier to microbial infection and enzymatic attack. Loss of
Kelly A Correll et al.
Biochemical and biophysical research communications, 499(4), 843-848 (2018-04-06)
TGF beta is a multifunctional cytokine that regulates alveolar epithelial cells as well as immune cells and fibroblasts. TGF beta inhibits surfactant protein A, B and C expression in fetal human lung and can inhibit type II cell proliferation induced
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.
Wesseling, J, et al.
Molecular Biology of the Cell, 7, 565-577 (1996)
Pablo Argüeso et al.
The Journal of biological chemistry, 284(34), 23037-23045 (2009-06-27)
Maintenance of an intact mucosal barrier is critical to preventing damage to and infection of wet-surfaced epithelia. The mechanism of defense has been the subject of much investigation, and there is evidence now implicating O-glycosylated mucins on the epithelial cell
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