Merck
所有图片(4)

文件

06-172-I

Sigma-Aldrich

Anti-Na+/K+ ATPase alpha-3

from rabbit

登录查看公司和协议定价

别名:
ATP1A3, Na+/K+ ATPase alpha-3, Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human

种属反应性(根据同源性预测)

mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

包装

antibody small pack of 25 μL

技术

immunohistochemistry: suitable (paraffin)
western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

ambient

靶向翻译后修饰

unmodified

基因信息

一般描述

Sodium/potassium-transporting ATPase subunit alpha-3 (UniProt: P06687; also known as EC: 3.6.3.9, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3) is encoded by the Atp1a3 gene (Gene ID: 24213) in rat. Sodium/potassium-transporting ATPase subunit alpha-3 is a multi-pass membrane protein that is exclusive to the brain tissue and is highly expressed in cell bodies and projections of hippocampus. It is responsible for establishing and maintaining the electrochemical gradients of sodium and potassium ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. Sodium/potassium-transporting ATPase subunit alpha-3 is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic component catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. Reduced levels of neuronal sodium/ potassium ATPase activity in ATP1A3 heterozygous mice increases their susceptibility to depression-like endophenotypes by chronic variable stress.

特异性

This rabbit polyclonal antibody detects Sodium/potassium-transporting ATPase subunit alpha-3 in human, mouse, and rat brain. It targets an epitope with in 25 amino acids from the N-terminal region.

免疫原

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to 25 amino acids from the N-terminal region of rat Sodium/potassium-transporting ATPase subunit alpha-3.

应用

Anti-Na+/K+ ATPase alpha-3, Cat. No. 06-172-I, is a highly specific rabbit polyclonal antibody that targets Sodium/potassium-transporting ATPase subunit alpha-3 and has been tested in Immunohistochemistry (Paraffin) and Western Blotting.
Immunohistochemistry Analysis: A 1:250-1,000 dilution of this antibody detected Na+/K+ ATPase alpha-3 in human cerebral cortex and human cardiac muscle tissue.
Research Category
Neuroscience

质量

Evaluated by Western Blotting in adult human brain tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Na+/K+ ATPase alpha-3 in 10 µg of adult human brain tissue lysate.

目标描述

~112 kDa observed; 111.75 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

外形

Affinity Purified
Format: Purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

为方便起见,与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码?

在网站页面上,产品编号会附带包装尺寸/数量一起显示(例如:T1503-25G)。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题?欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ (Lot或Batch)字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

  • 如果您查询到的批号含有填充代码(例如05427ES-021),请输入去除填充代码-021的批号:05427ES。

  • 如果您查询到的批号含有填充代码(例如 STBB0728K9),请输入去除填充代码K9的批号:STBB0728。

未找到您寻找的产品?

部分情况下,可能未在线提供COA。如果搜索不到COA,可在线索取。

索取COA

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门