Merck
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06-559

Sigma-Aldrich

Anti-Pyk2 Antibody

Upstate®, from rabbit

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eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

purified immunoglobulin

antibody product type

primary antibodies

克隆

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

target post-translational modification

unmodified

Gene Information

human ... PTK2B(2185)

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此商品
05-488-I07-892SAB4500836
Anti-Pyk2 Antibody Upstate®, from rabbit

Sigma-Aldrich

06-559

Anti-Pyk2 Antibody

Anti-Pyk2/CAKβ Antibody

Sigma-Aldrich

05-488-I

Anti-Pyk2/CAKβ Antibody

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

clone

polyclonal

clone

78, monoclonal

clone

polyclonal

clone

polyclonal

species reactivity

human, mouse

species reactivity

human, rat

species reactivity

human, rat

species reactivity

mouse, human, rat

manufacturer/tradename

Upstate®

manufacturer/tradename

-

manufacturer/tradename

Upstate®

manufacturer/tradename

-

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, western blot: suitable

technique(s)

ELISA: 1:10000, immunohistochemistry: 1:50-1:100

特异性

Recognizes Pyk2, and its degradation products; does not cross-react with FAK.

免疫原

GST-fusion protein containing amino acids 726-863 of human Pyk2

应用

Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling
This Anti-Pyk2 Antibody is validated for use in IC, IP, WB for the detection of Pyk2.

质量

routinely evaluated by immunoblot on mouse brain cytosolic RIPA lysates

目标描述

125 kDa

外形

Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain cytosolic RIPA lysates

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable


Certificates of Analysis (COA)

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25G
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Maja Beus et al.
ChemistryOpen, 7(8), 624-638 (2018-08-29)
We report the synthesis of SAHAquines and related primaquine (PQ) derivatives. SAHAquines are novel hybrid compounds that combine moieties of suberoylanilide hydroxamic acid (SAHA), an anticancer agent with weak antiplasmodial activity, and PQ, an antimalarial drug with low antiproliferative activity.
Mad3 negatively regulates B cell differentiation in the spleen by inducing Id2 expression.
Gore, Y; Lantner, F; Hart, G; Shachar, I
Molecular Biology of the Cell null
Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.
Ssang-Taek Lim,Nichol L G Miller,Ju-Ock Nam,Xiao Lei Chen,Yangmi Lim,David D Schlaepfer
The Journal of Biological Chemistry null
Shinichi Nakano et al.
Scientific reports, 9(1), 4236-4236 (2019-03-14)
Excessive osteoclastic bone erosion disrupts normal bone remodeling and leads to bone loss in many skeletal diseases, including inflammatory arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis, periodontitis and peri-prosthetic loosening. Functional control of osteoclasts is critical for the
Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level.
Daniela I Batovska,Dong Hoon Kim,Shinya Mitsuhashi,Yoon Sun Cho,Ho Jeong Kwon,Makoto Ubukata
Bioscience, Biotechnology, and Biochemistry null

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