ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis.
Sanchez-Moran, E; Santos, JL; Jones, GH; Franklin, FC
Genes & Development null
Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas.
Squatrito, M; Brennan, CW; Helmy, K; Huse, JT; Petrini, JH; Holland, EC
Cancer Cell null
Elena Llano et al.
Human molecular genetics, 23(13), 3421-3431 (2014-03-13)
Oligo- and azoospermia are severe forms of male infertility. However, known genetic factors account only for a small fraction of the cases. Recently, whole-exome sequencing in a large consanguineous family with inherited premature ovarian failure (POF) identified a homozygous frameshift...
Natalia I Dmitrieva et al.
American journal of physiology. Renal physiology, 285(2), F266-F274 (2003-04-10)
High NaCl causes DNA double-strand breaks and cell cycle arrest, but the mechanism of its genotoxicity has been unclear. In this study, we describe a novel mechanism that contributes to this genotoxicity. The Mre11 exonuclease complex is a central component...
Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments.
Karagiannis, TC; Harikrishnan, KN; Kn, H; El-Osta, A