Merck

1.03140

SAFC

Parteck SI 400 (山梨醇)

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF, FCC, JSFA, E 420

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别名:
Parteck®山梨糖醇
经验公式(希尔记法):
C6H14O6
CAS号:
分子量:
182.17
MDL编号:
E编号:
E420
EC索引号:
200-061-5

Agency

BP
JSFA
NF
Ph. Eur.

质量水平

管理合规性

FCC

产品线

EMPROVE® ESSENTIAL

形式

coarse powder

自燃温度

420 °C

质量

E 420

粒径

(see specification)

pH值(酸碱度)

6-7 (20 °C, 100 g/L in H2O)

mp

94-96 °C

转变温度

flash point >100 °C

溶解性

2350 g/L

密度

1.49 g/cm3 at 20 °C

应用

liquid formulation
pharmaceutical
solid formulation

储存温度

2-25°C

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2

InChI key

FBPFZTCFMRRESA-UHFFFAOYSA-N

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1.035571.075831.11597
vibrant-m

1.03140

Parteck SI 400 (山梨醇)

vibrant-m

1.03557

Parteck SI 450 (山梨醇)

vibrant-m

1.07583

Parteck®山梨糖醇

vibrant-m

1.11597

Parteck® SI 400 LEX(山梨糖醇)

form

coarse powder

form

coarse powder

form

fine powder

form

solid

mp

94-96 °C

mp

94-96 °C

mp

-

mp

94-96 °C

solubility

2350 g/L

solubility

2350 g/L

solubility

-

solubility

2350 g/L

storage temp.

2-25°C

storage temp.

2-25°C

storage temp.

-

storage temp.

2-25°C

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

500

一般描述

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Parteck® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

特点和优势

  • Excellent direct compression properties
  • High dilution and adsorption capacity
  • Larger and highly structured surface area
  • Low hygroscopicity
  • Low amount of reducing sugars

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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商品

This article describes the use of excipients to help address API stability issues.

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