1.03583

Parteck^®山梨糖醇

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF, JSFA, E 420

• Synonym(s): Parteck^® Sorbitol, D-Glucitol
• Empirical Formula (Hill Notation): C₆H₁₄O₆
• CAS Number: 50-70-4
• Molecular Weight: 182.17
• MDL编号: MFCD00004708
• E编号: E420

Properties

• Agency: BP; JP; JSFA; NF; Ph. Eur.
• 质量水平: 500
• 产品线: EMPROVE^® ESSENTIAL
• 形式: fine powder
• 自燃温度: 420 °C
• 粒径: (see specification)
• pH值（酸碱度）: 6-7 (20 °C, 100 g/L in H₂O)
• mp: 94-96 °C
• 转变温度: flash point >100 °C
• 溶解性: 2350 g/L
• 密度: 1.49 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• 储存温度: 2-25°C
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2
• InChI key: FBPFZTCFMRRESA-UHFFFAOYSA-N

Description

一般描述

With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck^® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Parteck^® SI excipient is a directly compressible sorbitol which combines excellent tableting behavior, resulting in very robust and shiny tablets, with a pleasant mouthfeel and taste. The unique and large surface area allows for a fast disintegration and dissolution, even at high tablet hardnesses and supports a good content uniformity of low dose API formulations. Parteck^® SI excipient comes in a variety of particle sizes and qualities to meet the needs of a very wide range of applications.

包装

2.5 kg in PE bottle

25 kg in PE bag (in carton)

储存及稳定性

Storage temperature: no restrictions.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(F): Not applicable
• 闪点(C): Not applicable