Stéphanie Rignault et al.
Critical care medicine, 33(6), 1302-1310 (2005-06-09)
A distinctive feature of sepsis is a pleiotropic modification of membrane protein expression in the vascular endothelium, associated with diminished endothelium-dependent relaxation (endothelial dysfunction). In cultured endothelial cells, inflammatory stimuli alter expression of connexins (Cx), proteins that make up the...
Spontaneous cardiac calcinosis in BALB/cByJ mice.
Glass, AM; Coombs, W; Taffet, SM
Comparative Medicine null
Adi D Dubash et al.
The Journal of cell biology, 212(4), 425-438 (2016-02-10)
Members of the desmosome protein family are integral components of the cardiac area composita, a mixed junctional complex responsible for electromechanical coupling between cardiomyocytes. In this study, we provide evidence that loss of the desmosomal armadillo protein Plakophilin-2 (PKP2) in...
Dakshesh Patel et al.
FEBS letters, 588(8), 1372-1378 (2014-01-18)
Connexin hemichannels are postulated to form a cell permeabilization pore for the uptake of fluorescent dyes and release of cellular ATP. Connexin hemichannel activity is enhanced by low external [Ca(2+)]o, membrane depolarization, metabolic inhibition, and some disease-causing gain-of-function connexin mutations....
Electrical stimulation systems for cardiac tissue engineering.
Tandon, N; Cannizzaro, C; Chao, PH; Maidhof, R; Marsano, A; Au, HT; Radisic, M; Vunjak-Novakovic, G
Nature Protocols null