Merck
所有图片(2)

文件

ABT123

Sigma-Aldrich

抗I型胶原抗体

from rabbit, purified by affinity chromatography

登录to View Organizational & Contract Pricing

别名:
Collagen alpha-1(I) chain, Alpha-1 type I collagen
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

species reactivity

mouse, rat

technique(s)

ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

target post-translational modification

unmodified

Gene Information

human ... COL1A1(1277)

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
ABT257ABT256AB755P
Anti-Collagen Type I Antibody from rabbit, purified by affinity chromatography

Sigma-Aldrich

ABT123

抗I型胶原抗体

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

mouse, rat

species reactivity

mouse, human

species reactivity

mouse, human, sheep

species reactivity

rat

technique(s)

ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), radioimmunoassay: suitable

NCBI accession no.

NP_445756

NCBI accession no.

NP_000079

NCBI accession no.

NP_000079

NCBI accession no.

NM_000088.3

Still not finding the right product?  

Give our Product Selector Tool a try.

一般描述

胶原在整个进化过程中是高度保守的,其特征在于不间断的“甘氨酸X Y”三联体重复序列,其是三螺旋结构的必需部分。I型胶原(95kDa)存在于骨骼,角膜,皮肤和肌腱中。编码基因的突变与成骨不全症,埃勒斯·当洛斯综合征和特发性骨质疏松症有关。该基因和血小板衍生的生长因子β基因所在的染色体17和22之间的相互易位与称为隆突性皮肤纤维肉瘤的特定类型的皮肤肿瘤有关,这是由于生长因子的表达不受调节所致。

免疫原

大鼠尾胶原

应用

使用经验证可用于蛋白质印迹、IHC(P)、ELISA的抗I型胶原抗体检测I型胶原。
特异性ELISA分析: 代表性批次在ELISA中检测到小鼠和大鼠胶原,但未检测到人胶原。

蛋白质印迹分析:代表性批次的1:2,000稀释液在10µg大鼠皮肤组织裂解物上检测到1型胶原。
研究子类别
粘附(CAMs)
研究类别
细胞结构

质量

通过免疫组化在大鼠皮肤组织中进行了评估。

免疫组化分析:该抗体的1:100稀释液在大鼠皮肤组织中检测到1型胶原。

目标描述

计算值为130 kDa

联系

替代品:AB755P

外形

亲和纯化
在含 0.1 M Tris-甘氨酸(pH 7.4),150 mM NaCl 和 0.05% 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。

储存及稳定性

自收到之日起,在 2-8°C 条件下可稳定保存1年

分析说明

对照
大鼠皮肤组织

其他说明

浓度:请参考批次特异性浓缩物的分析证书。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

在网站页面上,产品编号会附带包装尺寸/数量一起显示(例如:T1503-25G)。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题?欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ (Lot或Batch)字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

  • 如果您查询到的批号含有填充代码(例如05427ES-021),请输入去除填充代码-021的批号:05427ES。

  • 如果您查询到的批号含有填充代码(例如 STBB0728K9),请输入去除填充代码K9的批号:STBB0728。

未找到您寻找的产品?

部分情况下,可能未在线提供COA。如果搜索不到COA,可在线索取。

索取COA

其他客户在看

Slide 1 of 2

1 of 2

Yuqin Zhang et al.
Frontiers in pharmacology, 13, 937484-937484 (2022-10-04)
Ethnopharmacological relevance: Pien-Tze-Huang (PZH)-a traditional Chinese medicine (TCM) compound-has been employed to treat various liver inflammation and tumors for over 10 decades. Interestingly, most of the pharmacological effects had been validated and explored toward liver ailment along with pro-inflammatory conditions and
Fernanda Cristina de Mesquita et al.
Scientific reports, 7(1), 3255-3255 (2017-06-14)
Hepatic stellate cells (HSC) play a key role in the development of chronic liver disease (CLD). Liraglutide, well-established in type 2 diabetes, showed anti-inflammatory and anti-oxidant properties. We evaluated the effects of liraglutide on HSC phenotype and hepatic microvascular function
Lihua Cui et al.
Frontiers in pharmacology, 12, 679557-679557 (2021-06-29)
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) is a traditional Chinese medicine, which is widely used in the clinical treatment of digestive diseases. However, the potential anti-fibrosis mechanism of
Margherita Montorsi et al.
Biotechnology and bioengineering, 119(7), 1965-1979 (2022-04-07)
In the past decades, bone tissue engineering developed and exploited many typologies of bioreactors, which, besides providing proper culture conditions, aimed at integrating those bio-physical stimulations that cells experience in vivo, to promote osteogenic differentiation. Nevertheless, the highly challenging combination
Weidan Peng et al.
Molecular and cellular biology, 38(3) (2017-11-15)
Human antigen R (ELAVL1; HuR) is perhaps the best-characterized RNA-binding protein. Through its overexpression in various tumor types, HuR promotes posttranscriptional regulation of target genes in multiple core signaling pathways associated with tumor progression. The role of HuR overexpression in

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门