Merck
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AP160P

Sigma-Aldrich

兔抗小鼠IgG抗体,HRP偶联

Chemicon®, from rabbit

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eCl@ss:
32160702
NACRES:
NA.46

生物来源

rabbit

质量水平

偶联物

peroxidase conjugate

抗体形式

F(ab′)2 fragment of affinity isolated antibody

抗体产品类型

secondary antibodies

克隆

polyclonal

种属反应性

mouse

制造商/商品名称

Chemicon®

技术

ELISA: suitable
western blot: suitable

运输

wet ice

靶向翻译后修饰

unmodified

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vibrant-m

AP160P

兔抗小鼠IgG抗体,HRP偶联

vibrant-m

AP101P

兔抗人IgG抗体,HRP偶联

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

conjugate

peroxidase conjugate

species reactivity

mouse

species reactivity

mouse

species reactivity

mouse

species reactivity

human

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

technique(s)

ELISA: suitable, western blot: suitable

biological source

rabbit

biological source

rabbit

biological source

goat

biological source

rabbit

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

一般描述

免疫球蛋白G(IgG) 是在人类血清中发现的最丰富的糖蛋白抗体。它是由B细胞分泌的。IgG结构包含4条多肽链,其中包括两条相同的重(H)链和两条完全相同的λ轻(L)链。这些链通过二硫键相互连接。IgG以IgG1、IgG2、IgG3和IgG4四种亚型存在。

应用

兔抗小鼠IgG抗体,HRP偶联物已用于蛋白质印迹。(1:2000)(1:200000)(1:5000)

生化/生理作用

免疫球蛋白G(IgG)有助于补体系统的激活。它中和病毒颗粒和毒素。IgG促进抗体依赖性细胞介导的细胞毒性(ADCC)。母体IgG通过胎盘转移到 胎儿 ,这对于保护新生儿免受 传染病的侵害至关重要。检测严重急性呼吸系统综合征冠状病毒(SARS-CoV)2型感染患者的IgG水平可能是评估2019冠状病毒病(COVID-19)严重程度和预后的一种潜在策略。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Cristina Evangelisti et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4276-4287 (2009-08-29)
MicroRNAs are a class of sophisticated regulators of gene expression, acting as post-transcriptional inhibitors that recognize their target mRNAs through base pairing with short regions along the 3'UTRs. Several microRNAs are tissue specific, suggesting a specialized role in tissue differentiation
Elen Rizzi et al.
International journal of cardiology, 165(1), 165-173 (2011-09-16)
Increased oxidative stress upregulates matrix metalloproteinases (MMPs) and transforming grow factor (TGF-β), which are involved in hypertensive cardiac remodeling. We tested the hypothesis that tempol (an antioxidant) could prevent these alterations in two-kidney, one-clip (2K1C) hypertension. Sham-operated or hypertensive rats
Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury.
Roger S Chung, Paul A Adlard, Justin Dittmann, James C Vickers, Meng Inn Chuah, Adrian K West
Journal of Neurochemistry null
Rita L Peruquetti et al.
PloS one, 7(8), e42695-e42695 (2012-08-18)
Spermatogenesis is a complex differentiation process that involves genetic and epigenetic regulation, sophisticated hormonal control, and extensive structural changes in male germ cells. RNA nuclear and cytoplasmic bodies appear to be critical for the progress of spermatogenesis. The chromatoid body
S B A Cau et al.
British journal of pharmacology, 164(2), 372-381 (2011-03-26)
Mounting evidence implicates matrix metalloproteinase (MMP) in the vascular dysfunction and remodelling associated with hypertension. We tested the hypothesis that treatment with pyrrolidine dithiocarbamate (PDTC), which interferes with NF-κB-induced MMPs gene transcription, could exert antihypertensive effects, prevent MMP-2 and MMP-9

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