Merck
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FCMAB195F

Sigma-Aldrich

Milli-Mark® Anti-CD41-FITC Antibody, clone 5B12

clone 5B12, Milli-Mark®, from mouse

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别名:
Integrin alpha-IIb, Platelet membrane glycoprotein IIb, GPalpha IIb, GPIIb
eCl@ss:
32160702
NACRES:
NA.44

生物来源

mouse

质量水平

偶联物

FITC conjugate

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

5B12, monoclonal

种属反应性

human

制造商/商品名称

Milli-Mark®

技术

flow cytometry: suitable

同位素/亚型

IgG1κ

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ITGA2B(3674)

一般描述

CD41 is the α-subunit of the CD41/CD61 complex (GPIIb-IIIa), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-binding sites and is entirely extracellular, while the β-chain has extracellular, transmembrane, and cytoplasmic domains (Sun, 1997). The CD41/CD61 complex appears early in megakaryocyte maturation (Vinci, 1984). Anti-CD41, 5B12, was included in the Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD41 (Honda, 1995).

特异性

Antibody recognizes Human CD41 antigen.

免疫原

Normal human platelets

应用

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Milli-Mark Anti-CD41-FITC Antibody, clone 5B12 is validated for use in FC for the detection of CD41.

质量

Evaluated by flow cytometry using TF-1 cells

目标描述

135 kDa (Sun, 1997)

外形

Protein A purified
Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

储存及稳定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析说明

Control
TF-1 cells

法律信息

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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