Merck
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HCCBP2MAG-58K

Millipore

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 2 - Cancer Multiplex Assay

Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

所有图片(3)
eCl@ss:
32161000

质量水平

200

species reactivity

human

manufacturer/tradename

Milliplex®

assay range

accuracy: 92-107%
standard curve range: 0.01-50 ng/mL
(Extracellular matrix protein 1)
standard curve range: 0.48-2,000 ng/mL
(All other biomarkers)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

运输

wet ice

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HCCBP3MAG-58KHCCBP1MAG-58KHCMBMAG-22K
MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 2 - Cancer Multiplex Assay Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

Millipore

HCCBP2MAG-58K

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 2 - Cancer Multiplex Assay

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

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HCCBP3MAG-58K

MILLIPLEX® 人循环癌症生物标志物磁珠板3 - 癌症多重检测

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex Assay Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

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HCCBP1MAG-58K

MILLIPLEX® 人循环癌症生物标志物磁珠板 - 癌症多重检测

MILLIPLEX® Human Cancer/ Metastasis Biomarker Magnetic Bead Panel - Cancer Multiplex Assay Circulating Cancer and Metastasis Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

Millipore

HCMBMAG-22K

MILLIPLEX® 人癌症/转移生物标志物磁珠板 - 癌症多重检测

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

manufacturer/tradename

Milliplex®

assay range

accuracy: 92-107%, standard curve range: 0.01-50 ng/mL
(Extracellular matrix protein 1), standard curve range: 0.48-2,000 ng/mL
(All other biomarkers)

assay range

accuracy: 74-126%, standard curve range: 0.004-3 ng/mL
(Galectin-3), standard curve range: 0.02-20 ng/mL
(Myeloperoxidase), standard curve range: 0.03-25 nM
(Sex Hormone Binding Globulin), standard curve range: 0.03-25 ng/mL
(Ferritin), standard curve range: 0.07-50 ng/mL
(Catalase, Fibroblast Activation Protein α), standard curve range: 0.1-75 ng/mL
(Melanoma Inhibitory Activity Protein), standard curve range: 0.27-200 ng/mL
(Cathepsin D, IGFBP3)

assay range

accuracy: 35-108%, standard curve range: 0.09-67 mU/mL
(β-HCG), standard curve range: 0.7-500 pg/mL
(IL-6), standard curve range: 1.3-1000 pg/mL
(IL-8, TNFα), standard curve range: 2.7-2000 pg/mL
(TRAIL, TGF-α), standard curve range: 6.9-5000 pg/mL
(SCF)

assay range

accuracy: 70-105%, standard curve range: 0,019-80 ng/mL
(TRAP5), standard curve range: 0,048-20 ng/mL
(YKL40), standard curve range: 0.002-10 ng/mL
(GDF15), standard curve range: 0.007-30 ng/mL
(DKK-1), standard curve range: 0.007-30 ng/mL
(OPG), standard curve range: 0.036-150 ng/mL
(NSE), standard curve range: 0.195-800 ng/mL
(Periostin), standard curve range: 0.976-4,00 0 ng/mL
(Osteonectin (SPARC)), inter-assay cv: <16%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

detection method

fluorometric (Luminex xMAP)

detection method

fluorometric (Luminex xMAP)

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

一般描述

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

MILLIPLEX® Circulating Cancer Biomarker Panel 2 is a 4-plex kit that can be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, tissue/cell lysate and culture supernatant samples: Extracellular matrix Protein 1 (ECM1), Antithrombin III, Vitamin D binding protein, and Complement Factor H (CFH). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

应用

  • Analytes: Antithrombin III, Complement Factor H (CFH), Extracellular matrix Protein 1 (ECM1), Vitamin D binding protein
  • Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates
  • Note: Serum has a thrombin/antithrombin III complex bound to vitronectin. To accurately quantify antithrombin III concentrations we recommend using plasma samples because they lack the vitronectin/thrombin/antithrombin complex.
  • Recommended Sample Dilution: 25 μL of a 1:10,000 dilution of plasma or serum, or 25 μL of tissue/cell culture sample diluted in an appropriate control medium (dilution factors may vary)
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Cancer

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

组分

Human Circulating Cancer Biomarker Panel 2 Standard (HCC-8058-2)

Human Circulating Cancer Biomarker Panel 2 Quality Controls 1 and 2 (HCC-6058-2)

Set of one 96-Well Plate with 2 Sealers

Bead Diluent (LBD-4)

Assay Buffer (L-AB)
Note: Contains 0.08% Sodium Azide

10X Wash Buffer (L-WB)
Note: Contains 0.05% Proclin

Human Circulating Cancer Biomarker Panel 2 Detection Antibodies (HCC-1058)

Streptavidin-Phycoerythrin (L-SAPE 6)

其他说明

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

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Ginette Tardif et al.
Arthritis research & therapy, 24(1), 120-120 (2022-05-24)
Osteoarthritis (OA) is a slowly developing and debilitating disease, and there are no validated specific biomarkers for its early detection. To improve therapeutic approaches, identification of specific molecules/biomarkers enabling early determination of this disease is needed. This study aimed at

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Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

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