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MAB8701

Sigma-Aldrich

Anti-Dengue Virus Type I Antibody, clone 15F3-1

clone 15F3-1, Chemicon®, from mouse

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eCl@ss:
32160702

生物来源

mouse

质量水平

抗体形式

purified antibody

克隆

15F3-1, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

同位素/亚型

IgG1

运输

wet ice

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antibody form

purified antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

clone

15F3-1, monoclonal

clone

5D4-11, monoclonal

clone

3H5-1, monoclonal

clone

D3-2H2-9-21, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable, inhibition assay: suitable (hemagglutination)

technique(s)

immunocytochemistry: suitable, immunofluorescence: suitable

一般描述

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

特异性

Reacts with the Dengue type 1 virus. May show reactivity with Dengue type 2 virus.

免疫原

Dengue type 1 (Hawaiian) virus antigen.

应用

Anti-Dengue Virus Type I Antibody, clone 15F3-1 detects level of Dengue Virus Type I & has been published & validated for use in IF.
Immunofluorescent assay. Final working dilutions must be determined by end user.

外形

0.02M Phosphate Buffer, pH 7.6, 0.25M NaCl and 0.1% sodium azide.
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Sambashiva Banala et al.
ACS chemical biology, 8(10), 2127-2132 (2013-08-15)
Detection of antibodies is essential for the diagnosis of many diseases including infections, allergies, and autoimmune diseases. Current heterogeneous immunoassays require multiple time-consuming binding and washing steps, which limits their application in point-of-care diagnostics and high-throughput screening. Here, we report

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