Merck
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MAB8704

Sigma-Aldrich

Anti-Dengue Virus Type IV Antibody, clone 1H10-6

ascites fluid, clone 1H10-6, Chemicon®

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eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

ascites fluid

克隆

1H10-6, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
inhibition assay: suitable (hemagglutination)

同位素/亚型

IgG1

运输

dry ice

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1 of 4

此商品
MAB8702MAB8703MAB8701
antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

purified antibody

antibody form

purified antibody

clone

1H10-6, monoclonal

clone

3H5-1, monoclonal

clone

5D4-11, monoclonal

clone

15F3-1, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable, inhibition assay: suitable (hemagglutination)

technique(s)

immunofluorescence: suitable, inhibition assay: suitable (hemagglutination)

technique(s)

immunofluorescence: suitable

technique(s)

immunofluorescence: suitable

一般描述

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

特异性

Reacts with the Dengue type 4 virus.

免疫原

Dengue type 4 virus antigens (H241).

应用

Detect Dengue Virus Type IV using this Anti-Dengue Virus Type IV Antibody, clone 1H10-6 validated for use in IF, HI.
Immunofluorescent assay and hemagglutination-inhibition tests.

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

外形

Ascites

储存及稳定性

Maintain at -20°C for up to 12 months from date of receipt and avoid freeze/thaw cycles.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes.
Saima Khanam, Behzad Etemad, Navin Khanna, Sathyamangalam Swaminathan
The American Journal of Tropical Medicine and Hygiene null
An adenovirus type 5 (AdV5) vector encoding an envelope domain III-based tetravalent antigen elicits immune responses against all four dengue viruses in the presence of prior AdV5 immunity.
Khanam S, Pilankatta R, Khanna N, Swaminathan S
Vaccine null
Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies.
Gentry, M K, et al.
The American Journal of Tropical Medicine and Hygiene, 31, 548-555 (1982)
Dengue virus-specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence
Henchal, E A, et al
The American Journal of Tropical Medicine and Hygiene, 31, 830-836 (1982)

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