Merck
  • MABN369
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MABN369

Sigma-Aldrich

Anti-Neuroglobin Antibody, clone 6G1.1

clone 6G1.1, from mouse

Synonym(s):
Neuroglobin
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified immunoglobulin

antibody product type

primary antibodies

克隆

6G1.1, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

同位素/亚型

IgG2bκ

NCBI登记号

UniProt登记号

运输

wet ice

Gene Information

human ... NGB(58157)

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MABN1814MABN742MABN2185
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified antibody

clone

6G1.1, monoclonal

clone

7G4, monoclonal

clone

1C9.1, monoclonal

clone

6A7.2, monoclonal

species reactivity

human

species reactivity

mouse, rat

species reactivity

human, rat

species reactivity

human

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable (paraffin)

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

isotype

IgG2bκ

isotype

IgG2aκ

isotype

IgG2aκ

isotype

IgG2aκ

一般描述

Neuroglobin protein encoded by the gene NGB, is involved in oxygen transport in the brain. Neuroglobin is also important for neuroprotection during oxidative stress. Additionally, Neuroglobin has anti-apoptotic activity by reseting the mitochondrial membrane tigger level for cytochrome C release and the commitment to apoptosis. Neuroglobin is localized to the perikaryon, cytoplasm, and mitochondrion. Neuroglobin is predominantly expressed in the brain with strongest expression in the frontal lobe and the subthalamic nucleus and thalamus.

免疫原

GST-tagged recombinant protein corresponding to the N-terminus of human Neuroglobin.

应用

Detect Neuroglobin using this mouse monoclonal antibody, Anti-Neuroglobin Antibody, clone 6G1.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroglobin in human thalamus and human frontal lobe tissue.

质量

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroglobin in 10 µg of human cortex tissue lysate.

目标描述

~17 kDa observed

外形

Protein G Purified
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable


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