Merck
All Photos(1)

SCC008

Sigma-Aldrich

ReNcell VM人神经祖细胞系

ReNcell VM is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.

Synonym(s):
Human NSC Line, Human Neural Stem Cell Line, Human Neural Stem Cells
eCl@ss:
32011203

生物来源

human

质量水平

manufacturer/tradename

Chemicon®
ReNcell

technique(s)

cell culture | stem cell: suitable

input

sample type neural stem cell(s)

运输

liquid nitrogen

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biological source

human

biological source

human

biological source

human

biological source

human

manufacturer/tradename

Chemicon®, ReNcell

manufacturer/tradename

Chemicon®, ReNcell

manufacturer/tradename

Chemicon®, ReNcell

manufacturer/tradename

Chemicon®, ReNcell

technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | stem cell: suitable

shipped in

liquid nitrogen

shipped in

liquid nitrogen

shipped in

liquid nitrogen

shipped in

liquid nitrogen

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

input

sample type neural stem cell(s)

input

sample type neural stem cell(s)

input

sample type neural stem cell(s)

input

sample type neural stem cell(s)

一般描述

ReNcell VM是一种永生化的人神经祖细胞系,具有易于分化为神经元和神经胶质细胞的能力。 ReNcell VM源自人胎脑的腹侧中脑区域。 通过用v-myc癌基因进行逆转录病毒转导而永生化,该细胞系在层粘连蛋白上以单层快速生长,倍增时间为20-30小时。 核型分析表明,即使经过长时间传代(>45代),ReNcell VM仍可在培养物中保留正常的二倍体核型。 ReNcell VM由ReNeuron Group plc开发,ReNeuron Group plc是一家专门将人体体干细胞用于治疗的生物技术公司。 在ReNeuron Group plc进行的实验中,ReNcell VM可以在体外分化为高水平的人多巴胺能神经元。此外,已证明从ReNcell VM分化的神经元具有电生理活性。 ReNcell VM可用于多种研究应用,例如神经毒性、神经发生、电生理学、神经递质和受体功能的研究。 ReNcell Vm细胞是按照法律和伦理的方式获得的,符合现行的当地知情同意程序。

ReNcell现在用于阿尔茨海默′病的3D细胞模型!
Tanzi, R and Kim, DY et. al. A three-dimensional human neural cell culture model of Alzheimer′s disease.Nature.2014 Nov 13;515(7526):274-8.
发表在Nature上
产品来源:人腹侧中脑组织

细胞系描述

神经干细胞

应用

研究类别
干细胞研究

组分

来自人腹侧中脑组织的> 1x106个活ReNcell VM细胞,冷冻保存。 储存在液氮中。

质量

已经验证了每批ReNcell VM细胞的巢蛋白和Sox 2的高水平表达及其自我更新和多谱系分化能力。通过染色体扩散评估,细胞还显示出正常的核型,并且支原体测试为阴性。已对孕妇血液进行了HIV、HTLV、乙型和丙型肝炎筛查。

储存及稳定性

当在推荐的储存条件(液氮)下储存时,ReNcell VM细胞在有效期内保持稳定。 请勿暴露于高温下。 到期后,请丢弃所有剩余的试剂。 我们建议在十代内使用细胞。

其他说明

根据产品文件中详述的“学术使用协议”的条款,本产品预期仅用于销售和销售给学术机构,以供内部学术研究使用。有关任何其他用途的信息,请联系licensing@emdmillipore.com。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(F)

does not flash

闪点(C)

does not flash


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