SCT038

Sigma-Aldrich

BioTracker Orange OH and HClO Dye

new

Live cell imaging probe to detect hydroxy radical (OH) or hypochlorous acid (HClO) in live cells.

价格与库存信息目前不能提供

form

lyophilized

application(s)

cell analysis: suitable

detection method

fluorometric

General description

Reactive oxygen species (ROS) are important mediators in a variety of biological and pathological events. For example, ROS generated in mitochondria play important roles in the modulation of signal transduction cascades and transcription factors. However, oxidative stress due to excessive generation of ROS is implicated in many human diseases, including acute and chronic inflammatory processes, ischemic stroke, diabetes, sepsis, ischemia-reperfusion injury, atherosclerosis, and neurodegenerative disorders.BioTracker Orange OH and HClO Dye is an orange fluorescent probe to detect hydroxy radical (・OH) or hypochlorous acid (HClO) in live-cell imaging. It can detect -OH and HClO among other reactive oxygen species (O2-, H2O2, NO, ONOO-). Its nearly red fluorescence spectrum allows multicolor imaging with green (ex. GFP, FITC) and blue (ex. Hoechst 33342) fluorophores. Because of its positive charge, OxiORANGE tends to localize within mitochondria. It has high photostability and is suitable for time-lapse imaging of intracellular hROS generation.Spectral Properties:Absorbance (max): 553mEmission (max): 577nmResearch Category:Live Cell Dye

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

分析证书
原产地证书 (CofO)

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