03609

Sigma-Aldrich

乙二胺四乙酸

BioUltra, ≥99.0% (KT)

别名:
Ethylenedinitrilotetraacetic acid, 依地酸, EDTA, 亚乙基二次氮基四乙酸
线性分子式:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS号:
分子量:
292.24
Beilstein/REAXYS Number:
1716295
EC 号:
MDL编号:
eCl@ss:
39030907
PubChem化学物质编号:
NACRES:
NA.25

产品线

BioUltra

质量水平

300

测定

≥99.0% (KT)

形式

powder

杂质

insoluble matter, passes filter test

mp

250 °C (dec.) (lit.)

溶解性

0.1 M NaOH: 0.1 M at 20 °C, clear, colorless

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Al: ≤10 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in 1 M NaOH

紫外吸收

λ: 260 nm Amax: ≤1.00
λ: 280 nm Amax: ≤0.05

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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应用

乙二胺四乙酸 (EDTA) 是一种具有螯合二价阳离子(如钙和铯)能力的六齿配体和螯合剂。EDTA 广泛用于需要或使用隔离二价阳离子的领域。EDTA 用于人工限制性 DNA 切割工具的研究。

其他说明

阴离子和金属阳离子的测定采用单柱色谱法,以 EDTA 为淋洗液,采用电导法和紫外检测法 ;毛细管电泳 DNA 酶切分析中的缓冲液组分

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

hazcat

Eye Irrit. 2

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书

原产地证书 (CofO)

Yuichiro Aiba et al.
Chemical Society reviews, 40(12), 5657-5668 (2011-05-14)
This tutorial review provides recent developments in artificial cutters for site-selective scission of DNA with the focus on chemistry-based DNA cutters. They are useful tools for molecular biology and biotechnology, since their site-selectivity of scission is much higher than that...
S. Matsushita
Journal of Chromatography A, 312, 327-327 (1984)
A Paulus et al.
Electrophoresis, 14(1-2), 27-35 (1993-01-01)
DNA digest analysis with polymer-filled capillaries in capillary electrophoresis is described. The samples analyzed consisted of commercially available standards including a 100 base pair ladder with repeating units up to 2000 base pairs. Three DNA digests covered the most common...
Des R Richardson et al.
Journal of medicinal chemistry, 49(22), 6510-6521 (2006-10-27)
There has been much interest in the development of iron (Fe) chelators for the treatment of cancer. We developed a series of di-2-pyridyl ketone thiosemicarbazone (HDpT) ligands which show marked and selective antitumor activity in vitro and in vivo. In...
Cecilia Lezcano et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 27(9), 1193-1202 (2014-01-18)
Of more than 150 000 published studies evaluating new biomarkers, fewer than 100 biomarkers have been implemented for patient care. One reason for this is lack of rigorous testing by the medical community to validate claims for biomarker clinical relevance, and...

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