Merck
  • 17929
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17929

Sigma-Aldrich

O-Methyl-O′-succinylpolyethylene glycol 5′000

All Photos(2)
Synonym(s):
O-(Succinyl)-O′-methylpolyethylene glycol 5′000, Polyethylene glycol 5000 monomethyl ether succinate
Linear Formula:
CH3O(CH2CH2O)nCOCH2CH2COOH
CAS Number:
31961-02-1
MDL编号:
MFCD00284260
NACRES:
NA.26

形式

powder

质量水平

100

分子量

Mr ~5100

mp

56-60 °C

Ω端

carboxylic acid

α端

methoxy

储存温度

−20°C

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17928743127743011
O-Methyl-O′-succinylpolyethylene glycol 5′000

Sigma-Aldrich

17929

O-Methyl-O′-succinylpolyethylene glycol 5′000

O-Methyl-O′-succinylpolyethylene glycol 2′000

Sigma-Aldrich

17928

O-Methyl-O′-succinylpolyethylene glycol 2′000

O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 2,000

Sigma-Aldrich

743127

O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol

O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 10,000

Sigma-Aldrich

743011

O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol

form

powder

form

powder

form

solid

form

lumps

mol wt

Mr ~5100

mol wt

Mr ~2100

mol wt

average Mw 2,000

mol wt

average Mw 10,000

mp

56-60 °C

mp

50-53 °C

mp

-

mp

-

Ω-end

carboxylic acid

Ω-end

carboxylic acid

Ω-end

-

Ω-end

-

α-end

methoxy

α-end

methoxy

α-end

-

α-end

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

应用

Polyethylene glycol 5000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.
Soluble polymer for solid phase synthesis of imines and β-lactams; attaching peptides to PEG

生化/生理作用

O-Methyl-O′-succinylpolyethylene glycol 5′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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