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Merck

186562

Sigma-Aldrich

四氢呋喃

≥99.9%, anhydrous, contains 250 ppm BHT as inhibitor

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别名:
THF, 丁烯氧化物, 四亚甲基氧化物, 氧杂环戊烷
经验公式(希尔记法):
C4H8O
CAS号:
分子量:
72.11
Beilstein:
102391
EC號碼:
MDL號碼:
分類程式碼代碼:
12191501
PubChem物質ID:
NACRES:
NA.21

等級

anhydrous

品質等級

蒸汽密度

2.5 (vs air)

蒸汽壓力

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

化驗

≥99.9%

形狀

liquid

自燃溫度

610 °F

包含

250 ppm BHT as inhibitor

expl. lim.

1.8-11.8 %

雜質

≤0.005% peroxides (as H2O2)
<0.002% water (All units except 100 mL)
<0.005% water (100 mL pkg)

折射率

n20/D 1.407 (lit.)

pH值

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

溶解度

H2O: soluble

密度

0.889 g/mL at 25 °C (lit.)

SMILES 字串

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI 密鑰

WYURNTSHIVDZCO-UHFFFAOYSA-N

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一般說明

四氢呋喃(THF)是一种饱和环醚,主要用作有机溶剂。长期储存时,它会形成有机过氧化物。可通过添加丁基羟基甲苯(BHT)作为稳定剂而抑制这一过程。BHT能去除形成过氧化物所需的自由基。它是各种天然产物(聚醚类抗生素)的关键片段。THF可与硫化氢形成双水合物,其晶体结构已经过三维单晶研究法进行过研究。

應用

干燥四氢呋喃(THF)已用于合成二氯{双[1,1′,1′′-(膦三基)三哌啶]钯[(P(NC5H10)3)2Pd(Cl)2],广泛用作Heck反应中的催化剂。它已被用于各种芳基溴和烯烃的Heck交叉偶联反应介质。

其他說明

2-甲基四氢呋喃(414247)和环戊基甲基醚(675970)是许多THF应用更环保的替代选择。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

標靶器官

Central nervous system, Respiratory system

安全危害

水污染物質分類(WGK)

WGK 1

閃點(°F)

-6.2 °F

閃點(°C)

-21.2 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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