所有图片(4)

271004

Sigma-Aldrich

乙腈

anhydrous, 99.8%

别名:
乙腈, 甲基氰, 氰甲烷, ACN
线性分子式:
CH3CN
CAS号:
分子量:
41.05
Beilstein:
741857
EC 号:
MDL编号:
eCl@ss:
39031501
PubChem化学物质编号:
NACRES:
NA.21

质量水平

200

等级

anhydrous

蒸汽密度

1.41 (vs air)

蒸汽压

72.8 mmHg ( 20 °C)

测定

99.8%

形式

liquid

自燃温度

973 °F

expl. lim.

16 %

应用

solid phase extraction (SPE): suitable

杂质

<0.001% water
<0.005% water (100 mL pkg)

蒸发残留物

<0.0005%

颜色

colorless

折射率

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

溶解性

water: soluble (completely)

密度

0.786 g/mL at 25 °C (lit.)

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

正在寻找类似产品? Visit 产品对比指南

相关类别

一般描述

乙腈,一种脂肪腈,被广泛用作有机合成中的有机溶剂和中间体。它对紫外-可见光是透明的,这使其非常适用于基于分光光度和荧光的技术中。MeCN因具有低粘度、洗脱强度以及在水中的混溶性,而在许多色谱技术中被用作流动相组分。它还在液-液萃取、固相萃取或微萃取中作为萃取介质而起到了主要作用。

应用

乙腈可被用作溶剂用于制备:
  • 1,2-叠氮基醇和1,2-叠氮基胺,由叠氮化钠通过氯化铈(III)辅助的环氧化物和氮丙啶开环。
  • 在钯催化剂存在的情况下通过烯烃的氧化芳基烷基化得到含有偶氮基的吲哚酮。

它还可用作合成反应物:
  • 双(二苯基膦基)乙腈,通过与丁基锂反应以及随后与氯二苯基膦反应。
  • β-乙酰氨基酮,通过在氯化 II)钴的存在下与酮类或酮酯类和醛类的偶联反应。

包装

1, 6×1, 2, 4×2 L in Sure/Seal™
100, 12×100 mL in Sure/Seal™
200 L in Pure-Pac™ 1
18 L in Pure-Pac™ 1
20, 50 L in Pure-Pac™ 2

象形图

FlameExclamation mark

警示用语:

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK Germany

WGK 2

闪点(F)

35.6 °F - closed cup

闪点(C)

2.0 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

分析证书

原产地证书 (CofO)

Bis (diphenylphosphino) acetonitrile: Synthesis, ligand properties and application in catalytic carbon?carbon coupling
Braun L, et al.
Dalton Transactions, 14, 1409-1415 (2007)
Cobalt-catalysed three-component coupling involving ketones or ketoesters, aldehydes and acetonitrile: a novel one-pot synthesis of ?-acetamido ketones
Madhavaa Reddy M.
Journal of the Chemical Society. Chemical Communications, 6, 713-714 (1994)
Eagleson M.
Concise Encyclopedia Chemistry, 56-56 (1994)
Palladium-Catalyzed Oxidative Arylalkylation of Activated Alkenes: Dual C-H Bond Cleavage of an Arene and Acetonitrile.
Wu T, et al.
Angewandte Chemie (International Edition in English), 50(52), 12578-12581 (2011)
Cerium (III) chloride promoted highly regioselective ring opening of epoxides and aziridines using NaN3 in acetonitrile: a facile synthesis of 1,2-azidoalcohols and 1,2-azidoamines.
Sabitha G, et al.
Organic Letters, 4(3), 343-345 (2002)

技术文章

Greener Chemistry: Methods and Products for Amide Bond Formation

Amide bonds are ubiquitous in both nature and industrial applications. They are vital to the structure and function of biological macromolecules and polymers. The importance of this functionality has resulted in numerous approaches to its formation, ranging from stoichiometric activation of carboxylic acids to more recent advances in catalytic amide bond formation.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门