Merck
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文件

63187

Sigma-Aldrich

甲氧基聚乙二醇马来酰亚胺

≥90% (NMR), 5,000

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别名:
MeO-PEG-Mal, PEG-马来酰亚胺, 单甲基聚乙二醇 2-马来酰亚胺乙醚
CAS号:
99126-64-4
MDL编号:
MFCD00803681
PubChem化学物质编号:
24882458
NACRES:
NA.25

质量水平

200

检测方案

≥90% (NMR)

分子量

PEG average Mn 5,000

Ω端

maleimide

α端

methoxy

储存温度

−20°C

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此商品
71255871246985973
Methoxypolyethylene glycol maleimide ≥90% (NMR), 5,000

Sigma-Aldrich

63187

甲氧基聚乙二醇马来酰亚胺

Methoxypolyethylene glycol maleimide 750

Sigma-Aldrich

712558

甲氧基聚乙二醇马来酰亚胺

Methoxypolyethylene glycol maleimide PEG average Mn 10.000

Sigma-Aldrich

712469

甲氧基聚乙二醇马来酰亚胺

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester ≥80%

Supelco

85973

甲氧基聚乙二醇 5,000 乙酸 N-琥珀酰亚胺基酯

mol wt

PEG average Mn 5,000

mol wt

PEG average Mn 750

mol wt

PEG average Mn 10.000

mol wt

PEG average Mn 5,000

Ω-end

maleimide

Ω-end

maleimide

Ω-end

maleimide

Ω-end

NHS ester

α-end

methoxy

α-end

methoxy

α-end

methoxy

α-end

methoxy

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

应用

甲氧基聚乙二醇马来酰亚胺（MeO-PEG-Mal）用作蛋白质聚乙二醇化试剂。聚乙二醇化是将聚乙二醇（PEG）聚合物链共价连接到蛋白质等其他分子上的过程。

相关产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Sigma-Aldrich

JKA7029

4臂-PEG20K-马来酰亚胺

Poly(ethylene glycol) methyl ether average Mn 5,000

Sigma-Aldrich

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聚乙二醇甲基醚

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Methoxypolyethylene glycol p-nitrophenyl carbonate average mol wt 5,000

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K Ananda et al.
Analytical biochemistry, 374(2), 231-242 (2007-12-27)
The design of the extension arm-facilitated PEGylation (EAFP) of proteins takes advantage of the high selective and quantitative aspects of the thiol-maleimide reaction. However, the efficiency of EAFP with hemoglobin varied with the batches of maleimide-PEG. The low level of
R J Goodson et al.
Bio/technology (Nature Publishing Company), 8(4), 343-346 (1990-04-01)
We have modified recombinant interleukin-2 (rIL-2) to facilitate site-directed covalent attachment of monomethoxy polyethylene glycol (PEG). The site chosen for modification and subsequent covalent attachment with PEG (PEGylation) was the single glycosylation position found in the native interleukin-2 (IL-2). The
Jiankun Qie et al.
Drug metabolism letters, 1(3), 232-240 (2007-08-01)
Site-specific mono-PEGylations were performed in different conformational regions of Thymosin alpha 1 (T alpha 1) by introducing one cysteine residue into the chosen site and coupling with thiol-specific mPEG-MAL reagent. Results demonstrated that PEGylated sites and regions influenced the conformations
Lidia Wrobel et al.
Scientific reports, 6, 27484-27484 (2016-06-07)
Disulfide bond formation is crucial for the biogenesis and structure of many proteins that are localized in the intermembrane space of mitochondria. The importance of disulfide bond formation within mitochondrial proteins was extended beyond soluble intermembrane space proteins. Tim22, a
Leah C Ray et al.
Nature chemical biology, 14(6), 538-541 (2018-05-18)
Polyprenol phosphate phosphoglycosyl transferases (PGTs) catalyze the first membrane-committed step in assembly of essential glycoconjugates. Currently there is no structure-function information to describe how monotopic PGTs coordinate the reaction between membrane-embedded and soluble substrates. We describe the structure and mode
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