Merck
All Photos(4)

A7085

Sigma-Aldrich

对乙酰氨基酚

BioXtra, ≥99.0%

Synonym(s):
4′-羟基乙酰苯胺, 4-乙酰氨基酚, N-(4-羟基苯基)乙酰胺, N-乙酰基-4-氨基苯酚, APAP, 扑热息痛
Linear Formula:
CH3CONHC6H4OH
CAS Number:
Molecular Weight:
151.16
Beilstein:
2208089
EC 号:
MDL编号:
PubChem化学物质编号:

产品线

BioXtra

质量水平

200

测定

≥99.0%

形式

powder

杂质

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

灼烧残渣

≤0.1%

mp

168-172 °C (lit.)

溶解性

ethanol: 0.5 M, clear, colorless

痕量阴离子

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

一般描述

对乙酰氨基酚或扑热息痛是一种止痛和退烧药。然而,其是一种弱的非阿片类镇痛药。

应用

对乙酰氨基酚已被用于:
  • 作为抗炎药以测试其在海洋贻贝中脂质过氧化作用中的作用
  • 测试其对γ-氨基丁酸能和谷氨酸能神经元神经突生长的影响
  • 作为小鼠肝细胞损伤诱导剂

镇痛剂。

包装

100, 500 g in glass bottle
1 kg in glass bottle

生化/生理作用

对乙酰氨基酚或扑热息痛是一种前列腺素合成的抑制剂。它在中枢神经系统中可与花生四烯酸复合,导致形成N-花生四烯酰苯酚胺,这对于激活大麻素受体至关重要。对乙酰氨基酚会被代谢为有毒的N-乙酰基-对-苯醌亚胺。扑热息痛已被用于治疗骨关节炎,并抑制环氧合酶1和2的活性。它可在肝脏中被细胞色素P450酶代谢,与肝脏毒性有关。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

364.3 °F - Pensky-Martens closed cup

闪点(C)

184.6 °C - Pensky-Martens closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service