Merck
All Photos(6)

B2883

Sigma-Aldrich

双苯并咪唑 H 33258

≥98% (HPLC and TLC)

Synonym(s):
BBIH, BXI-72, HOE 33258, Hoechst 33258, NSC334072, 烟酸己可碱 三盐酸盐, 甲嗪双苯咪酚 三盐酸盐
Empirical Formula (Hill Notation):
C25H24N6O · 3HCl
CAS Number:
Molecular Weight:
533.88
Beilstein:
4088183
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.47

质量水平

检测方案

≥98% (HPLC and TLC)

形式

powder

mp

280 °C

溶解性

H2O: 10 mg/mL
water and ethanol: 10 mg/mL
phosphate buffer: precipitates

适用性

passes application test for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

储存温度

−20°C

SMILES string

Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6

InChI

1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2

InChI key

OWRSPPSBNWJJAR-UHFFFAOYSA-N

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This Item
D800114530B1155
assay

≥98% (HPLC and TLC)

assay

≥97% (HPLC)

assay

≥98.0% (HPLC)

assay

≥98% (HPLC and TLC)

form

powder

form

powder

form

powder

form

powder

solubility

H2O: 10 mg/mL, water and ethanol: 10 mg/mL, phosphate buffer: precipitates

solubility

-

solubility

water and ethanol: 10 mg/mL, H2O: soluble, ethanol: soluble

solubility

H2O: 10 mg/mL, water and ethanol: 10 mg/mL

storage temp.

−20°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mp

280 °C

mp

175-177 °C (lit.)

mp

-

mp

-

应用

bisBenzimide H 33258可用于DNA、染色体和细胞核的染色。 bisBenzimide H 33258可用于荧光显微术或流式细胞术。
最大激发波长= 346nm
最大发射波长= 460nm
bisBenzimide H 33258已用于细胞中的核染色。

生化/生理作用

bisBenzimide H 33258是一种有效的选择性Bcl-XL抑制剂。 bisBenzimide H 33258是一种膜可渗透的荧光DNA染色剂,具有低细胞毒性,可嵌入DNA的A-T区域。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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