推荐产品
等級
pharmaceutical primary standard
API 家族
bicalutamide
形狀
solid
儲存期限
limited shelf life, expiry date on the label
製造商/商標名
BP
應用
pharmaceutical
pharmaceutical small molecule
格式
neat
儲存溫度
2-8°C
SMILES 字串
CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C#N)c(c2)C(F)(F)F
InChI
1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChI 密鑰
LKJPYSCBVHEWIU-UHFFFAOYSA-N
基因資訊
human ... AR(367)
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Bicalutamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Bicalutamide Tablets
Also used in monographs such as:
生化/生理作用
比卡鲁胺 (CDX) 是一种非杀菌的雄激素受体 (AR) 拮抗剂,是纯抗雄激素。它通过平衡组蛋白乙酰化/去乙酰化和共调剂募集发挥作用。比卡鲁胺(CDX)消除了雄激素介导的表达。例如,前列腺癌、PLZF(早幼粒细胞白血病锌指蛋白)和GADD45γ中的MMP13上调(生长停滞和可诱导的DNA损伤,γ)。通过雄激素,对PI3K /AKT磷酸化进行非基因组、非转录依赖性刺激,抑制比卡鲁胺(CDX)。
包裝
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
其他說明
Sales restrictions may apply.
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Aquatic Chronic 1 - Carc. 2 - Repr. 1B
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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