E2503000

依托咪酯

European Pharmacopoeia (EP) Reference Standard

• 别名: (R)-1-(α-甲苄基)咪唑-5-甲酸乙酯, Amidate, R16659
• 经验公式（希尔记法）: C₁₄H₁₆N₂O₂
• CAS Number: 33125-97-2
• 分子量: 244.29
• MDL號碼: MFCD00869295
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329799031
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: etomidate
• 製造商／商標名: EDQM
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: CCOC(=O)c1cncn1[C@H](C)c2ccccc2
• InChI: 1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
• InChI 密鑰: NPUKDXXFDDZOKR-LLVKDONJSA-N
• 基因資訊: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Etomidate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化／生理作用

依托咪酯(Etomidate)是一种全身麻醉药；可激活GABA_A 信号通路

依托咪酯(Etomidate)是一种全身麻醉药；可激活GABAA信号通路。已有研究，依托咪酯对大鼠脑和脊髓中链脲菌素诱导(STZ-induced)的高血糖具有神经保护作用。依托咪酯治疗对神经组织具有抗糖尿病氧化损伤的神经保护作用。

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H302,H410
• 防範說明: P273 - P301 + P312 + P330
• 危險分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable