Merck
All Photos(8)

E7750

Sigma-Aldrich

N-(3-二甲基氨基丙基)-N'-乙基碳二亚胺 盐酸盐

commercial grade, powder

Synonym(s):
N-乙基-N′ -(3-二甲基氨基丙基)碳二亚胺 盐酸盐, EDAC, EDC, EDC 盐酸盐, WSC 盐酸盐
Empirical Formula (Hill Notation):
C8H17N3 · HCl
CAS Number:
Molecular Weight:
191.70
Beilstein:
5764110
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.31

等级

commercial grade

质量水平

300

形式

powder

mp

110-115 °C (lit.)

溶解性

H2O: ≤100 mg/mL

储存温度

−20°C

SMILES string

Cl.CCN=C=NCCCN(C)C

InChI

1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

InChI key

FPQQSJJWHUJYPU-UHFFFAOYSA-N

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应用

  • N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐已用于荧光纳米钻石(FND)-转铁蛋白生物偶联物的形成。[1]
  • 它已用于聚乙烯亚胺与金颗粒的交联。[2]
  • 它已用作碳二亚胺键合剂,用于将生物素化的BSA(牛血清白蛋白)涂覆在羧化的聚苯乙烯微珠上。[3]

包装

100 mg in poly bottle
1, 5, 10, 25, 100 g in poly bottle
1, 5 kg in poly drum

生化/生理作用

水溶性缩合试剂。EDAC通常用作与伯胺进行酰胺键合的羧基活化剂。另外,它能与磷酸基团反应。其已用于例如肽合成、将蛋白质与核酸交联、以及免疫缀合物的制备。通常,EDAC在不含缓冲剂的pH范围4.0-6.0的条件下使用。特别是,应避免使用胺和羧酸盐缓冲液。

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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