Merck

G0625

Sigma-Aldrich

D -(+)-半乳糖

≥98% (HPLC)

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别名:
半乳糖
Empirical Formula (Hill Notation):
C6H12O6
CAS号:
分子量:
180.16
Beilstein:
1724619
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.21

生物来源

bovine (Ruminant- Cow, Ox, Buffalo)

质量水平

检测方案

≥98% (HPLC)

形式

powder

technique(s)

HPLC: suitable
cell based assay: suitable

颜色

white to off-white

useful pH range

5.0-7 (25 °C, 180 g/L)

mp

168-170 °C (lit.)

溶解性

water: 180 g/L at 20 °C (68 °F )

application(s)

cell analysis
genomic analysis
life science and biopharma

储存温度

room temp

SMILES string

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1

InChI key

GZCGUPFRVQAUEE-KCDKBNATSA-N

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D-(+)-Galactose ≥98% (HPLC)

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D-(+)-Galactose ≥99%

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D -(+)-半乳糖

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Galactose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1206

D -(+)-半乳糖

-
assay

≥98%

assay

≥99%

assay

≥99%

assay

-

form

powder

form

powder

form

powder

form

-

technique(s)

HPLC: suitable, cell based assay: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white to off-white

color

-

color

white

color

-

useful pH range

5.0-7 (25 °C, 180 g/L)

useful pH range

-

useful pH range

5.0-7 (25 °C, 180 g/L)

useful pH range

-

一般描述

D-半乳糖是葡萄糖的 C-4 外聚体,是一种关键的哺乳动物单糖,广泛存在于血液、牛奶、神经节苷脂以及 N 和 O 链聚糖中。它普遍存在于植物和动物中,并作为多种多糖的组成部分,包括半乳甘露聚糖、卡拉胶、琼脂(L-半乳糖)、半纤维素和半乳多糖。作为一种醛己糖,它是糖脂和糖蛋白的能量来源和关键元素。D-半乳糖经过酶促转化为 D-葡萄糖进行代谢或多糖储存,代表葡萄糖的 C-4 表聚体。

此外,半乳糖是双糖乳糖的基本成分,通过 β-半乳糖苷酶水解释放,在细菌的生存和毒力中起着至关重要的作用。在大肠杆菌中,半乳糖通过 Leloir 途径起效,其中 β-d-半乳糖作为碳源,β-d-半乳糖诱导 UDP-半乳糖合成以实现生物合成糖基化。半乳糖可用于研究代谢紊乱,如半乳糖血症,并作为参与半乳糖分解代谢的酶的底物,使其成为半乳糖转移酶标记缓冲液的重要成分和 MRS 肉汤中促进嗜热乳酸菌生长的补充物。

应用

D-(+)-半乳糖已用于:
  • 用作SGal 培养基补充剂培养酵母菌株,以检查不同 SSA 热休克蛋白 (Hsp70) 亚型在 Hsp90 伴侣功能中的作用
  • 用作Biolog (MT2) 微孔板测定中的碳源,测试分离物利用碳底物的能力
  • 诱导酵母中膜蛋白-绿色荧光蛋白 (GFP) 融合表达

D-半乳糖是一种能量来源和代谢物,在细胞生物学、代谢组学和生物化学研究中有广泛的应用。

生化/生理作用

D-半乳糖代谢导致形成活性氧 (ROS) ,并导致氧化压力和肝细胞损伤。
半乳糖是一种简单的单糖,可作为能量来源,也是糖脂和糖蛋白的必需成分。半乳糖被Leloir途径的酶转化为葡萄糖,从而能够促进能量代谢。缺乏编码这些蛋白质的基因,将导致代谢功能紊乱疾病半乳糖血症。

特点和优势

  • 非常适合代谢组学、生物学和生化研究
  • 用途广泛,适用于各种实验室和研究应用。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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