Merck
All Photos(4)

G6529

Sigma-Aldrich

L -还原型谷胱甘肽

BioXtra, ≥98.0%

Synonym(s):
γ-L-谷酰基-L-半胱氨酰-甘氨酸, GSH
Linear Formula:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
CAS Number:
Molecular Weight:
307.32
Beilstein:
1729812
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.26

产品线

BioXtra

质量水平

检测方案

≥98.0%

形式

powder

杂质

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

灼烧残渣

≤0.1%

颜色

white

mp

192-195 °C (dec.) (lit.)

溶解性

H2O: 0.1 M, clear, colorless

痕量阴离子

sulfate (SO42-): ≤0.05%

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.02%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

储存温度

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

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1 of 4

This Item
G6013G42511.04090
Glutathione (reduced) suitable for biopharmaceutical production EMPROVE® bio Ph Eur

SAFC

1.04090

谷胱甘肽(还原型)

product line

BioXtra

product line

BioReagent

product line

-

product line

EMPROVE® Bio

assay

≥98.0%

assay

≥98.0%

assay

≥98.0%

assay

-

form

powder

form

powder

form

powder

form

-

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

-

impurities

-

impurities

-

color

white

color

white

color

white

color

-

mp

192-195 °C (dec.) (lit.)

mp

192-195 °C (dec.) (lit.)

mp

192-195 °C (dec.) (lit.)

mp

185-195 °C

Amino Acid Sequence

γ-Glu-Cys-Gly

应用

可在5-10 mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。

生化/生理作用

作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。 谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。 谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。 经由这些机制,它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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