Merck

PHR1012

Supelco

对羟基苯甲酸甲酯

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
4-羟基苯甲酸甲酯, 对羟基苯甲酸甲酯, 对羟苯甲酸甲酯, 尼泊金甲酯
线性分子式:
HOC6H4CO2CH3
CAS号:
分子量:
152.15
Beilstein:
509801
EC 号:
MDL编号:
PubChem化学物质编号:
E编号:
E218
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to Ph. Eur. M1650000
traceable to USP 1432005

API family

parabens

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

125-128 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

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此商品
M8911H6654H5501
Methylparaben Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1012

对羟基苯甲酸甲酯

-
Methyl 4-hydroxybenzoate analytical standard

Sigma-Aldrich

M8911

4-羟基苯甲酸甲酯

-
Methyl 4-hydroxybenzoate BioXtra, ≥99.0% (titration)

Sigma-Aldrich

H6654

4-羟基苯甲酸甲酯

Premium Grade
Methyl 4-hydroxybenzoate ReagentPlus®, ≥99.0%, crystalline

Sigma-Aldrich

H5501

4-羟基苯甲酸甲酯

-
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

-

format

neat

format

-

format

-

format

-

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

一般描述

对羟基苯甲酸甲酯是一种抗真菌剂和抗菌剂,广泛用于化妆品、药品、食品和饮料领域。
药物二级标准品CRM,为制药行业QC实验室及生产质量控制和研发,提供了一种方便、高性价比且符合相关法规的替代方案。

应用

对羟基苯甲酸甲酯可用作药物参考标准品,用于通过反相序贯进样色谱法(SIC)和高效液相色谱技术量化制药配方中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

分析说明

这些二级标准品可追溯至USP、EP(PhEur)和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

要查看该材料的分析证书示例,请在下面的栏位中输入LRAC0280。这只是一个示例证书,可能不是您收到的批次。

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Environment

危险声明

预防措施声明

危险分类

Aquatic Chronic 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

334.4 °F

闪点(C)

168 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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示例

T1503
货号
-
25G
包装规格/数量

其它示例:

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PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column
Satinsky D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(2), 287-293 (2006)
A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation
Kokoletsi XM, et al.
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Simultaneous determination of methylparaben, propylparaben, hydrocortisone acetate and its degradation products in a topical cream by RP-HPLC.
Hajkova R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 32(4-5), 921-927 (2003)
Gabriela Oliveira et al.
International journal of pharmaceutics, 435(1), 38-49 (2012-05-29)
Simple topical formulations which include volatile components, such as gels or sprays, are appealing from a cosmetic perspective. However, complex formulation effects may result from the use of volatile excipients in topical formulations, particularly when applied at clinically relevant doses
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Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the

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