PHR1729

盐酸丁丙诺啡

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 丁丙诺啡标准液 盐酸盐
• Empirical Formula (Hill Notation): C₂₉H₄₁NO₄ · HCl
• CAS Number: 53152-21-9
• Molecular Weight: 504.10
• EC 号: 258-396-8
• MDL编号: MFCD00084836
• PubChem化学物质编号: 329823578
• NACRES: NA.24

Properties

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to Ph. Eur. Y0001109; traceable to USP 1078700
• CofA: current certificate can be downloaded
• 包装: pkg of 50 mg
• drug control: USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• 格式: neat
• 储存温度: 2-30°C
• SMILES string: Cl[H].CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4CC7CC7)c56
• InChI: 1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1
• InChI key: UAIXRPCCYXNJMQ-RZIPZOSSSA-N

Description

一般描述

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Buprenorphine Hydrochloride is a potent long-acting synthetic opiate analgesic.

应用

Buprenorphine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

Full agonist at ORL1 receptors, antagonist or partial agonist at μ, κ, and δ opioid receptors.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7438 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• 象形图: GHS07,GHS08
• 警示用语：: Warning
• 危险声明: H302 - H361
• 预防措施声明: P201 - P301 + P312 + P330 - P308 + P313
• 危险分类: Acute Tox. 4 Oral - Repr. 2
• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 3
• 闪点(F): Not applicable
• 闪点(C): Not applicable