PHR1729

盐酸丁丙诺啡

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 丁丙诺啡标准液 盐酸盐
• 经验公式（希尔记法）: C₂₉H₄₁NO₄ · HCl
• CAS号: 53152-21-9
• 分子量: 504.10
• EC號碼: 258-396-8
• MDL號碼: MFCD00084836
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823578
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to Ph. Eur. Y0001109; traceable to USP 1078700
• API 家族: buprenorphine
• CofA: current certificate can be downloaded
• 包裝: pkg of 50 mg
• 藥物控制: USDEA Schedule III; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: Cl[H].CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4CC7CC7)c56
• InChI: 1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1
• InChI 密鑰: UAIXRPCCYXNJMQ-RZIPZOSSSA-N

说明

一般說明

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Buprenorphine Hydrochloride is a potent long-acting synthetic opiate analgesic.

應用

Buprenorphine Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

Full agonist at ORL1 receptors, antagonist or partial agonist at μ, κ, and δ opioid receptors.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7438 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H302,H361
• 防範說明: P201 - P301 + P312 + P330 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Repr. 2
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable