T5411

Supelco

睾酮 溶液

1.0 mg/mL in 1,2-dimethoxyethane, drug standard

CAS号:
Beilstein/REAXYS Number:
1915399
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

等级

drug standard

质量水平

200

drug control

Home Office Schedule 4.2

浓度

1.0 mg/mL in 1,2-dimethoxyethane

应用

HPLC: suitable
gas chromatography (GC): suitable

格式

single component solution

储存温度

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@@H](O)CC[C@@]24[H]

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI key

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

1 mL in ampule

警示用语:

Danger

补充剂危害

EUH019

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

RIDADR

UN 2252 3 / PGII

WGK Germany

WGK 1

闪点(F)

41.0 °F - closed cup

闪点(C)

5 °C - closed cup

Julia K Slezak et al.
Scientific reports, 7(1), 17636-17636 (2017-12-17)
The concentrations of testosterone deposited in hair during hair growth may provide a retrospective reflection of the concentrations of bioactive testosterone in plasma. The objective of this study was to develop a radioimmunoassay with a sufficiently low limit of detection...
Jenny Roy et al.
Bioorganic & medicinal chemistry, 15(8), 3003-3018 (2007-03-06)
In our efforts to develop compounds with therapeutic potential as antiandrogens, we synthesized a series of 5alpha-androstane-3alpha,17beta-diol derivatives with a fixed side-chain length of 3-methylenes at C-16alpha, but bearing a diversity of functional groups at the end. Among these, the...
Annu A Söderholm et al.
Journal of medicinal chemistry, 48(4), 917-925 (2005-02-18)
We studied the three-dimensional quantitative structure-activity relationships (3D QSAR) of 70 structurally and functionally diverse androgen receptor (AR) binding compounds using the comparative molecular similarity indices analysis (CoMSIA) method. The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and...
Line Cantin et al.
The Journal of biological chemistry, 282(42), 30910-30919 (2007-08-23)
Antiandrogens are commonly used to treat androgen-dependent disorders. The currently used drugs unfortunately possess very weak affinity for the human AR (hAR), thus indicating the need to develop new high-affinity steroidal antiandrogens. Our compounds are specially designed to impede repositioning...
Peng Cui et al.
Bioorganic & medicinal chemistry letters, 16(13), 3401-3405 (2006-05-03)
Lisofylline (LSF, 1-(5-R-hydroxyhexyl)-3,7-dimethylxanthine) is an anti-inflammatory agent that protects beta-cells from Th1 cytokine-induced dysfunction and reduces the onset of Type 1 diabetes in non-obese diabetic (NOD) mice. Due to its low potency, poor oral bioavailability, and short half-life, the widespread...

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