Merck

01930

Sigma-Aldrich

腺苷 5'-单磷酸 二钠盐

≥99.0% (HPLC)

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别名:
5′-AMP二钠盐,, 腺苷酸二钠盐, 5′-AMP-Na2
经验公式(希尔记法):
C10H12N5Na2O7P
CAS号:
分子量:
391.18
Beilstein:
3586732
EC 号:
MDL编号:
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51

生物来源

microbial (Candida utilis)
synthetic

检测方案

≥99.0% (HPLC)

形式

powder

旋光性

[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)

杂质

≤26% water

SMILES string

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

QGXLVXZRPRRCRP-IDIVVRGQSA-L

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A26209A1752A6885
vibrant-m

01930

腺苷 5'-单磷酸 二钠盐

vibrant-m

A26209

腺苷 5'-三磷酸 二钠盐 水合物

vibrant-m

A1752

腺苷-5'-单磷酸 钠盐

form

powder

form

-

form

powder

form

powder

biological source

microbial (Candida utilis)

biological source

-

biological source

yeast

biological source

-

optical activity

[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)

optical activity

-

optical activity

-

optical activity

-

impurities

≤26% water

impurities

-

impurities

-

impurities

-

应用

5′-单磷酸腺苷二钠盐已用于:

  • 作为可溶性有机磷(DOP)化合物,以研究在大肠杆菌裂解物中的水解速率
  • 诱导Fura2成骨细胞(C2-OB)钙反应
  • 在分离、培养和鉴定胶质瘤干细胞(GSC)的培养基中作为核苷酸代谢物
腺苷5′-一磷酸(5′-AMP)在自然界中具有许多用途。5′-AMP是一类蛋白激酶[AMP活化蛋白激酶(AMPK)]的激活剂。它可以用作多种酶的底物,如AMP-胸苷激酶(EC 2.7.1.114)、AMP脱氨酶(EC 3.5.4.6)和5′-核苷酸酶(EC 3.1.3.5)。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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实验方案

Separation of AMP (adenosine monophosphate); ATP (adenosine triphosphate)

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