Merck

118R-1

Sigma-Aldrich

CD38 (SP149) Rabbit Monoclonal Antibody

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NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

culture supernatant

antibody product type

primary antibodies

克隆

SP149, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

species reactivity

human

包装

vial of 0.1 mL concentrate (118R-14)
vial of 0.5 mL concentrate (118R-15)
bottle of 1.0 mL predilute (118R-17)
vial of 1.0 mL concentrate (118R-16)
bottle of 7.0 mL predilute (118R-18)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG

控制

bone marrow, lymph node, plasma cell myeloma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

Gene Information

human ... CD38(952)

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138R-2134R-1134M-1
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

clone

SP149, monoclonal

clone

EP201, monoclonal

clone

EP88, monoclonal

clone

QBEnd/10, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

一般描述

CD38 molecule is a 46-kDa type-II transmembrane glycoprotein with a short N-terminalcytoplasmic tail (20 amino acids) and a long extracellular domain (256 amino acids). Itis present on many hematopoietic cells, especially plasma cells, and in some solid tumortissues. CD38 is one of the early expressed markers of mature naive B-cell activation and it isuseful in identifying functional mature B-lymphocyte subsets.

质量


IVD

IVD

IVD

RUO

联系

CD38 Positive Control Slides, Product No. 118S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Certificates of Analysis (COA)

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T1503
货号
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25G
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Leoncini, L et al. Burkitt lymphoma. In Swerdlow SH, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, WHO Press, Lyon, France, 2008; 262-264.
Leoncini, L
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 262-264 (2008)
M Dono et al.
Journal of immunology (Baltimore, Md. : 1950), 164(11), 5596-5604 (2000-05-23)
The VH4 genes expressed by both resting and in vivo-activated subepithelial (SE) B cells from human tonsils were studied. Resting SE B cells were subdivided according to the presence (IgDlow) or absence (IgM-only) of surface IgD. CD27 was abundant on
Fabio Malavasi et al.
Physiological reviews, 88(3), 841-886 (2008-07-16)
The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of enzymes that play crucial roles in human physiology. Expressed in distinct patterns in most tissues, CD38 (and CD157) cleaves NAD(+) and NADP(+), generating cyclic ADP ribose (cADPR)
Leoncini, L et al. Burkitt lymphoma. In Swerdlow SH, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, WHO Press, Lyon, France, 2008; 262-264.
Leoncini, L
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 262-264 (2008)
Sandeep S Dave et al.
The New England journal of medicine, 354(23), 2431-2442 (2006-06-09)
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma. Tumor-biopsy specimens from 303 patients with

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