Merck

168M-9

Sigma-Aldrich

CD68 (Kp-1) Mouse Monoclonal Antibody

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NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

antibody product type

primary antibodies

克隆

Kp-1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

species reactivity

human

包装

vial of 0.1 mL concentrate (168M-94)
vial of 0.5 mL concentrate (168M-95)
bottle of 1.0 mL predilute (168M-97)
vial of 1.0 mL concentrate (168M-96)
bottle of 7.0 mL predilute (168M-98)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1κ

控制

tonsil

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

Gene Information

human ... CD68(968)

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108M-9263M-1161M-1
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

culture supernatant

antibody form

diluted ascites fluid

antibody form

diluted ascites fluid

antibody form

culture supernatant

clone

Kp-1, monoclonal

clone

C8/144B, monoclonal

clone

NKI/C3, monoclonal

clone

2f2, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

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一般描述

Anti-CD68 marks cells of monocyte/macrophage lineage. This antibody is capable of staining monocytes, Kupffer cells, osteoclasts, granulocytes and their precursors; lymphomas are negative or show a few granules. This antibody may be useful for the identification of myelomonocytic and histiocytic tumors. Anti-CD68 may help to distinguish malignant fibrous histiocytoma from other pleomorphic sarcomas. However, since this detects a formalin-resistant epitope that may be associated with lysosomal granules, other lysosome-rich cells may also stain.

质量


IVD

IVD

IVD

RUO

联系

CD68 Positive Control Slides, Product No. 168S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

分析证书(COA)

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L Martinez-Pomares et al.
Immunobiology, 195(4-5), 407-416 (1996-10-01)
Monoclonal antibodies directed against murine macrophage differentiation antigens provide tools to characterize novel glycoproteins, their expression by different macrophage subpopulations in situ and regulation by cytokines and other agents in vitro. Studies are in progress to determine ligands for these
CD68 cluster workshop report
JL Cordell, et al.
Leucocyte Typing V, 925-927 (1995)
L P Ruco et al.
American journal of clinical pathology, 92(3), 273-279 (1989-09-01)
The expression of macrophage antigens KP1, Mac, lysozyme, and alpha-1-antichymotrypsin was investigated on routine paraffin sections from 17 cases of Langerhans' cell histiocytosis (LCH). All the major clinical forms were represented, including single lesions and monosystemic and multisystemic disease. In
J L Snow et al.
The British journal of dermatology, 133(1), 71-76 (1995-07-01)
The clinical, histopathological, and immunophenotypic characteristics of four cases of malignancy-associated multicentric reticulohistiocytosis (MMR) and one case each of diffuse cutaneous reticulohistiocytosis (DCR) and isolated reticulohistiocytoma (IR), are reviewed. In all four cases of MMR the cutaneous lesions and joint
F Facchetti et al.
Histopathology, 19(2), 141-145 (1991-08-01)
The monoclonal antibody KP1, which recognizes the CD 68 antigen on macrophages and myeloid precursors, was tested on 28 malignant (primary and metastatic) melanomas, 28 naevi, and 17 skin biopsies showing either normal (10) or hyperplastic melanocytes (7). Sixteen of

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