Merck
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文件

210R-1

Sigma-Aldrich

Prolactin (EP193) Rabbit Monoclonal Primary Antibody

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NACRES:
NA.41

生物来源

rabbit

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

antibody product type

primary antibodies

克隆

EP193, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形式

buffered aqueous solution

species reactivity

human

包装

bottle of 1.0 mL predilute (210R-17)
bottle of 7.0 mL predilute (210R-18)
vial of 0.1 mL concentrate (210R-14)
vial of 0.5 mL concentrate (210R-15)
vial of 1.0 mL concentrate (210R-16)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG

运输

wet ice

储存温度

2-8°C

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482R-1486R-1268R-1
Prolactin (EP193) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

210R-1

Prolactin (EP193) Rabbit Monoclonal Primary Antibody

p63 (EP174) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

482R-1

p63 (EP174) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

Sigma-Aldrich

486R-1

Somatostatin Receptor 2A (EP149) Rabbit Monoclonal Primary Antibody

IgD (EP173) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

268R-1

IgD (EP173) Rabbit Monoclonal Primary Antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

IgG fraction of antiserum

antibody form

culture supernatant

clone

EP193, monoclonal

clone

EP174

clone

EP149

clone

EP173, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

一般描述

Prolactin (PRL) is a single-chain polypeptide of 226 amino acids with a molecular weight of about 24 kD. Prolactin plays a role in multiple processes including cell growth, reproduction, and immune function.1 The pituitary hormone PRL is involved in tumorigenesis in rodents and humans. PRL promotes proliferation, survival, and migration of cancer cells acting via the PRL receptor.5 Anti-prolactin is a useful marker in classification of pituitary tumors and the study of pituitary disease as it reacts with prolactin-producing cells.2-4 Such prolactin-producing cells can also be found in prostate epithelium.5

质量


IVD
IVD
IVD
RUO

联系

Prolactin Positive Control Slides, Product No. 210S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Certificates of Analysis (COA)

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M T Nevalainen et al.
The Journal of clinical investigation, 99(4), 618-627 (1997-02-15)
Prolactin is widely expressed in different tissues, and it is presumed to have both local and systemic actions. In males it is known to influence reproductive functions but the significance and mechanisms of prolactin action in male accessory reproductive tissues
S L Asa et al.
Archives of pathology & laboratory medicine, 106(7), 360-363 (1982-07-01)
Sixty adult human pituitary glands taken at autopsy were stained for prolactin using the immunoperoxidase technique, and percentages of prolactin-bearing cells were assessed. There was no difference between the percentages of prolactin cells seen in the adenohypophyses of adult men
Giuseppe Minniti et al.
Surgical neurology, 57(2), 99-103 (2002-03-21)
Prolactinomas invading the skull base are rare, and could easily be confused with skull base tumors of nonpituitary origin. We report a series of 4 cases of giant prolactinomas invading the skull base and presenting with atypical symptoms. Case 1
T M Duello et al.
The American journal of anatomy, 158(4), 463-469 (1980-08-01)
Among 92 surgically removed pituitary adenomas immunostained for prolactin and growth hormone, 70 showed positive staining for prolactin. The majority of these (54) was associated with hyperprolactinemia leading to amenorrhea (and often galactorrhea) in women of reproductive age. Similar tumors
A Popadić et al.
Surgical neurology, 51(1), 47-54 (1999-02-10)
Malignant prolactinomas are rare events. To date, only 14 patients with metastases in- or outside the central nervous system have been reported. We present a patient who developed a metastasis to the cauda equina, which is the first case documented

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