Merck

30030

Sigma-Aldrich

罗布麻苷

≥96% (HPLC)

别名:
K-Strophanthidin-D-cymaroside, K-Strophanthin-α
Empirical Formula (Hill Notation):
C30H44O9
CAS号:
分子量:
548.66
Beilstein:
101370
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥96% (HPLC)

SMILES string

CO[C@H]1C[C@@H](O[C@H](C)[C@H]1O)O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6

InChI

1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1

InChI key

XQCGNURMLWFQJR-ZNDDOCHDSA-N

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此商品
PHL89838PHL83215PHL80207
Cymarin ≥96% (HPLC)

Sigma-Aldrich

30030

罗布麻苷

Cymarin phyproof® Reference Substance

PHL89838

罗布麻苷

Strophanthidin phyproof® Reference Substance

PHL83215

毒毛旋花子苷元

g-Strophanthin phyproof® Reference Substance

PHL80207

g-Strophanthin

应用

Cymarin was used to study the effect of cardiac glycosides on vascular smooth muscles and ion transport.

生化/生理作用

Cymarin is a cardiac glycoside and is classified as cardiotonic steroid. It inhibits ion transport by decreasing the activity of (Na-K)-ATPase.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 2

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificates of Analysis (COA)

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E V Lopatina et al.
Bulletin of experimental biology and medicine, 146(6), 744-746 (2009-06-11)
We studied the role of cardiac glycosides in the regulation of the growth of retinal tissue explants from 10-12-day-old chicken embryos in organotypic culture. The studied compounds produced a dose-dependent effect on cell proliferation in retinal tissue explants. Ouabain (10(-13)M)
Z B Skorzova et al.
Sudebno-meditsinskaia ekspertiza, 32(2), 35-36 (1989-04-01)
Private technique of extraction isolation and purification, chromatographic detection and photometric determination of zimarin in urine is suggested. Detection limit is 0.01 mg, determination limit is 0.1 mg of glycoside in 100 ml of urine. Method makes it possible to
Iu I Pivovarov et al.
Biulleten' eksperimental'noi biologii i meditsiny, 96(8), 24-28 (1983-08-01)
Experiments on rats were made to study the character of rhythmical activity of intact heart and heart with abnormal reactivity under electrical stimulation of the blue spot (BS) and formation in it of the generator of pathologically enhanced excitation (GPEE)
Increased in vivo synthesis of retinal Na pump isoforms after pre-treatment with citrate buffer.
S C Specht et al.
Progress in clinical and biological research, 268B, 143-147 (1988-01-01)
C Giunta et al.
General pharmacology, 16(3), 183-188 (1985-01-01)
Ouabain and K-strophanthoside promote an enhancement of Na+/K+-ATPase activity in a range of cardioglycoside concentrations from 100 nM to 100 pM, with a maximum (+30%) between 10 and 4 nM. Binding experiments with [3H]ouabain show upward-curved Scatchard plots and evidence

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