Merck
All Photos(1)

30200

Sigma-Aldrich

L -胱氨酸

≥99.7% (TLC)

Synonym(s):
(R,R)-3,3′-亚二硫基二(2-丙氨酸)
Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS Number:
Molecular Weight:
240.30
Beilstein:
1728094
EC 号:
MDL编号:
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

质量水平

200

测定

≥99.7% (TLC)

形式

powder or crystals

旋光性

[α]20/D −219±5°, c = 1% in 1 M HCl

灼烧残渣

≤0.1% (as SO4)

缺失

≤0.1% loss on drying

颜色

white

mp

>240 °C (dec.) (lit.)

溶解性

1 M HCl: 0.5 g/10 mL, clear, colorless

痕量阴离子

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤6 mg/kg
Fe: ≤10 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤150 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

peptide synthesis

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

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应用

L-胱氨酸已被用于制备原液,该原液又通过光谱荧光流动注射法用于测定药物制剂以及尿液样品中的L-半胱氨酸和L-胱氨酸。[1]

生化/生理作用

胱氨酸是合成保护细胞免受氧化应激的谷胱甘肽所必需的。一种特殊的 x (c)-半胱氨酸/谷氨酸反向转运蛋白可介导细胞摄取半胱氨酸以交换谷氨酸。[2]半胱氨酸摄取抑制诱导神经元细胞毒性。[3]

其他说明

用于 N,N′-二苯甲酰基-L-胱氨酸的制备,酮不对称还原的高效辅助剂[4][5]

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

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