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322M-1

Podoplanin (D2-40) Mouse Monoclonal Antibody

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NACRES:

NA.41

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1 of 4

此商品	320M-1	238M-9	334M-8
Sigma-Aldrich 322M-1 Podoplanin (D2-40) Mouse Monoclonal Antibody	Sigma-Aldrich 320M-1 Cytokeratin 20 (Ks20.8) Mouse Monoclonal Antibody	Sigma-Aldrich 238M-9 Chromogranin A (LK2H10) Mouse Monoclonal Antibody	Sigma-Aldrich 334M-8 Cytokeratin (34betaE12) Mouse Monoclonal Antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form culture supernatant	antibody form culture supernatant	antibody form culture supernatant	antibody form culture supernatant
clone D2-40, monoclonal	clone Ks20.8, monoclonal	clone LK2H10, monoclonal	clone 34betaE12, monoclonal
form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution	form buffered aqueous solution
species reactivity human	species reactivity human	species reactivity human	species reactivity human

一般描述

Podoplanin is a transmembrane mucoprotein (38 kD) recognized by the D2-40 monoclonal antibody. Podoplanin is selectively expressed in normal and malignant lymphatic endothelium, including Kaposi’s sarcomas. Podoplanin has also been shown to be expressed in epithelioid mesotheliomas and seminomas.

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Podoplanin Positive Control Slides, Product No. 322S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

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产品编号

说明

价格

322S

Podoplanin Positive Control Slides, suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections)

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

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705578-5MG-PW

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1000309185

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Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas.

Folker E Franke et al.

Journal of cutaneous pathology, 31(5), 362-367 (2004-04-03)

Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial

Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40.

F Fogt et al.

Oncology reports, 11(1), 47-50 (2003-12-05)

Distribution of lymphatic vessels in normal and neoplastic colon has been previously analyzed with electron microscopic techniques, as reliable antibodies have not been available for selective lymph vessel staining. A novel monoclonal antibody, D2-40, is recently available to differentiate lymphatic

D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma.

Nelson G Ordóñez

Human pathology, 36(4), 372-380 (2005-05-14)

Recent investigations have shown that podoplanin and the D2-40 monoclonal antibody, which reacts with an oncofetal antigen present in fetal germ cells, are highly reliable lymphatic endothelial markers. The observation that both of these markers are also expressed in normal

Podoplanin: a novel diagnostic immunohistochemical marker.

Nelson G Ordóñez

Advances in anatomic pathology, 13(2), 83-88 (2006-05-04)

Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable

Identification of lymphatic endothelium in pediatric vascular tumors and malformations.

Csaba Galambos et al.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 8(2), 181-189 (2005-02-19)

The distinction between lymphatic and other vascular vessels on microscopic sections is a challenging task. D2-40, a novel antibody, has been reported to be selective for lymphatic endothelium. We studied the specificity and sensitivity of D2-40 in pediatric vascular tumors

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Podoplanin (D2-40) Mouse Monoclonal Antibody

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