404R-1

C4d (SP91) Rabbit Monoclonal Antibody

• NACRES: NA.41

Properties

• 生物来源: rabbit
• 质量水平: 100; 500
• 偶联物: unconjugated
• 抗体形式: culture supernatant
• antibody product type: primary antibodies
• 克隆: SP91, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形式: buffered aqueous solution
• species reactivity: human
• 包装: vial of 0.1 mL concentrate (404R-14); vial of 0.5 mL concentrate (404R-15); bottle of 1.0 mL predilute (404R-17); vial of 1.0 mL concentrate (404R-16); bottle of 7.0 mL predilute (404R-18)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• 同位素/亚型: IgG
• 控制: lymph node, tonsil
• 运输: wet ice
• 储存温度: 2-8°C
• 可视化: cytoplasmic, membranous
• Gene Information: human ... C4B(721)

Description

一般描述

C4d is a stable split product remnant of classical complement activation which becomes covalently bound to endothelium and basement membrane after induction of the classical antibody-induced pathway. As an established marker of antibody-mediated acute renal allograft rejection (AR) and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be closely correlated with transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of AR that may serve to warrant prompt and aggressive anti-rejection treatment.

包装

0.1, 0.5, 1, 7 mL

质量

IVD

IVD

IVD

RUO

联系

C4d Positive Control Slides, Product No. 404S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 2
• 闪点(F): Not applicable
• 闪点(C): Not applicable