453R-1

p53 (SP5) Rabbit Monoclonal Antibody

• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100; 500
• 偶联物: unconjugated
• 抗体形式: culture supernatant
• antibody product type: primary antibodies
• 克隆: SP5, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形式: buffered aqueous solution
• species reactivity: human
• 包装: vial of 0.1 mL concentrate (453R-14); vial of 0.5 mL concentrate (453R-15); bottle of 1.0 mL predilute (453R-17); vial of 1.0 mL concentrate (453R-16); bottle of 7.0 mL predilute (453R-18)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• 同位素/亚型: IgG1
• 控制: colon carcinoma
• 运输: wet ice
• 储存温度: 2-8°C
• 可视化: nuclear
• Gene Information: human ... TP53(7157)

说明

一般描述

Anti-p53 tumor suppressor protein antibody recognizes a 53 kDa phosphoprotein, identified as p53 suppressor gene product. It reacts with the mutant as well as wild type p53, although significant accumulation of the mutant form of p53 protein due to longer half-life half-life is the basis for the test using the IHC technique. Quantitation of nuclear staining with this antibody has been shown to be a factor in breast carcinoma, lung carcinoma, colorectalcarcinoma, urothelial carcinoma, and ependymoma. p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.

联系

p53 Positive Control Slides, Product No. 453S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 2
• 闪点(F): Not applicable
• 闪点(C): Not applicable