所有图片(1)

46951

Sigma-Aldrich

荧光素异硫氰酸酯异构体I

≥97.5% (HPLC)

别名:
FITC, 荧光素5-异硫氰酸酯
Empirical Formula (Hill Notation):
C21H11NO5S
CAS号:
分子量:
389.38
Beilstein:
1407295
EC 号:
MDL编号:
PubChem化学物质编号:

质量水平

100

测定

≥97.5% (HPLC)

形式

powder

杂质

≤1.5% Isomer II

mp

>360 °C (lit.)

溶解性

acetone: soluble 0.1 g/10 mL

荧光

λex 492 nm; λem 518 nm (green)
λex 492 nm; λem 518 nm in 0.1 M phosphate pH 8.0

储存温度

2-8°C

SMILES string

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(ccc45)N=C=S)c1

InChI

1S/C21H11NO5S/c23-12-2-5-16-18(8-12)26-19-9-13(24)3-6-17(19)21(16)15-4-1-11(22-10-28)7-14(15)20(25)27-21/h1-9,23-24H

InChI key

MHMNJMPURVTYEJ-UHFFFAOYSA-N

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应用

用于蛋白FITC标记的试剂;蛋白和肽的微测序(HPLC)

象形图

Health hazard

警示用语:

Danger

危险声明

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

分析证书

原产地证书 (CofO)

T Matthes et al.
Leukemia, 29(9), 1901-1908 (2015-03-11)
Multiple myeloma (MM) is a non-curable tumor developing in the bone marrow (BM). The BM microenvironment rich in hematopoietic precursors is suspected to have a role in MM development. Here we show that a proliferation-inducing ligand (APRIL) mediated in vivo...
Aram Ghalali et al.
Carcinogenesis, 35(7), 1547-1555 (2014-01-24)
Epidemiological studies indicate that statins, cholesterol-lowering drugs, prevent aggressive prostate cancer and other types of cancer. Employing essentially non-prostate cell lines, we previously showed that statins rapidly downregulate nuclear levels of phosphorylated Akt via P2X7, a purinergic receptor recently implicated...
Wenhuo Hu et al.
Blood, 125(14), 2206-2216 (2015-01-31)
Hematopoietic stem cells (HSCs) possess the ability to generate all hematopoietic cell types and to self-renew over long periods, but the mechanisms that regulate their unique properties are incompletely understood. Herein, we show that homozygous deletion of the miR-29a/b-1 bicistron...
Marina Vivarelli et al.
Kidney international, 87(3), 602-609 (2015-01-08)
Alloimmune antenatal membranous nephropathy (MN) during pregnancy results from antibodies produced by a neutral endopeptidase (NEP)-deficient mother. Here we report two recent cases that provide clues to the severity of renal disease. Mothers of the two children had circulating antibodies...
Benoit Malleret et al.
Blood, 125(8), 1314-1324 (2014-11-22)
Plasmodium vivax merozoites only invade reticulocytes, a minor though heterogeneous population of red blood cell precursors that can be graded by levels of transferrin receptor (CD71) expression. The development of a protocol that allows sorting reticulocytes into defined developmental stages...

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