Merck
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75746

Sigma-Aldrich

十二烷基硫酸钠

≥99.0% (GC), dust-free pellets

Synonym(s):
SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠
Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
Molecular Weight:
288.38
Beilstein:
3599286
EC 号:
MDL编号:
eCl@ss:
39093306
PubChem化学物质编号:
NACRES:
NA.25

描述

anionic

检测方案

≥99.0% (GC)

形式

rod

分子量

average mol wt 18,000

聚集数

62

缺失

≤5% loss on drying

CMC

7-10 (lit.)

mp

204-207 °C (lit.)

转变温度

cloud point >100 °C(lit.)

溶解性

H2O: soluble 0.29 gm in 10ml, clear, colorless
H2O: 0.1 M at 20 °C, clear, colorless

痕量阴离子

chloride (Cl-): ≤200 mg/kg

痕量阳离子

Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤200 mg/kg
Mg: ≤20 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

40(lit.)

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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十二烷基硫酸钠

description

anionic

description

anionic

description

anionic

description

anionic

assay

≥99.0% (GC)

assay

≥99.0% (GC)

assay

≥99.0% (GC)

assay

≥98.5% (GC)

form

rod

form

powder

form

-

form

-

mol wt

average mol wt 18,000

mol wt

micellar avg mol wt 18,000

mol wt

micellar avg mol wt 18,000

mol wt

micellar avg mol wt 18,000

aggregation number

62

aggregation number

62

aggregation number

62

aggregation number

62

CMC

7-10 (lit.)

CMC

7-10 mM (20-25°C)

CMC

7-10 mM (20-25°C)

CMC

7-10 mM (20-25°C)

一般描述

十二烷基硫酸钠(SDS)是一种离子洗涤剂,包含一个极性硫酸盐头基和一个疏水12-碳链。

应用

十二烷基硫酸钠(SDS)已用于:
  • 带负电荷的表面活性剂,研究其在表面活性剂稳定乳液的微滤期间对过滤通量和膜污染的影响
  • 植物提取缓冲液和传递缓冲液的组分用于蛋白质印迹
  • 5× Laemmli样品缓冲液(5× LB)和10×SDS运行缓冲液的组分,以进行十二烷基硫酸钠聚丙烯酰胺凝胶电泳(SDS-PAGE)和免疫印迹

阴离子洗涤剂

生化/生理作用

十二烷基硫酸钠(SDS)通过硫酸基团和烷基链有效地与蛋白质的正电荷和疏水残基结合。在结构生物学和蛋白质折叠/去折叠研究中,它是一种重要的清洁剂。SDS可刺激蛋白质结果中α-螺旋链的产生。它具有促进多种蛋白质,包括牛血清蛋白(BSA)、β-乳球蛋白、α-乳清蛋白和蛋清溶菌酶等,在高浓度下的协同去折叠能力。 

象形图

CorrosionExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(F)

338.0 °F

闪点(C)

170 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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