Merck

818M-9

Sigma-Aldrich

Cytokeratin 8 & 18 (B22.1 & B23.1) Mouse Monoclonal Antibody

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NACRES:
NA.41

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

diluted ascites fluid

抗体产品类型

primary antibodies

克隆

B22.1 & B23.1, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形式

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (818M-94)
vial of 0.5 mL concentrate (818M-95)
bottle of 1.0 mL predilute (818M-97)
vial of 1.0 mL concentrate (818M-96)
bottle of 7.0 mL predilute (818M-98)

制造商/商品名称

Cell Marque

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1κ

控制

prostate, salivary gland

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

基因信息

human ... KRT8(3856)

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此商品
356M-1905H-0356R-1
species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

biological source

mouse

biological source

mouse

biological source

mouse, rabbit

biological source

rabbit

clone

B22.1 & B23.1, monoclonal

clone

D5 & 16B4, monoclonal

clone

EP1601Y + LL002, monoclonal

clone

EP24 & EP67, monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

一般描述

Cytokeratins 8 &18 (CK 8 & 18) are major components of the intermediate filaments in the thyroid, liver, and most simple epithelia (e.g. breast, gastrointestinal and respiratory tracts). Anti-CK 8 & 18 is found to stain most adenocarcinomas and squamous cell carcinomas. CK8 & 18 are frequently used as the epithelial markers for identifying Paget cells, metastatic gastric, and colorectal carcinomas.

质量


IVD

IVD

IVD

RUO

联系

Cytokeratin 8 & 18 Positive Control Slides, Product No. 818S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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T1503
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J M Corson
Pathology annual, 21 Pt 2, 47-81 (1986-01-01)
Keratin protein immunohistochemistry is a powerful diagnostic tool whose role has already been firmly established in many surgical pathology laboratories. Recent studies of the biology of keratin proteins have defined the heterogeneity of keratin protein expression among various epithelial tissues
B Angus et al.
The Journal of pathology, 153(4), 377-384 (1987-12-01)
Production of a new monoclonal antibody designated NCL-5D3 is described. The antibody recognizes several low molecular weight cytokeratins, in particular cytokeratin Moll number 8 as determined by immunoblotting studies, and is highly effective for immunocytochemistry using routinely processed paraffin-embedded material.
M Sasaki et al.
Histopathology, 32(3), 199-208 (1998-05-06)
Recent reports suggest that genetic examination of K-ras or p53 mutation is more sensitive for the detection of occult lymph node metastasis in colorectal carcinomas than conventional examination by haematoxylin and eosin (H & E) staining or immunohistochemistry for gene

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