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Merck

A2522

Sigma-Aldrich

肌动蛋白 来源于兔肌肉

≥85% (SDS-PAGE), lyophilized powder

别名:

Alpha-actin 1, G-Actin

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

rabbit

品質等級

化驗

≥85% (SDS-PAGE)

形狀

lyophilized powder

分子量

43 kDa

成份

Protein, ≥80% biuret

技術

immunoblotting: suitable

UniProt登錄號

儲存溫度

2-8°C

基因資訊

rabbit ... LOC(100342017)

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一般說明

肌动蛋白在许多细胞中含量丰富,约占总蛋白的10%或更多。研究显示,大多数真核细胞中存在肌动蛋白。肌动蛋白有外部结构域和内部结构域两个重要结构域。

應用

从兔肌肉中提取的肌动蛋白可用作:
  • 研究其对兔肌肉乳酸脱氢酶的保护作用,使该酶免受抗坏血酸抑制
  • 作为 SDS 凝胶和免疫印迹的标准品
  • 蛋白微针阵列测定

生化/生理作用

肌动蛋白在蛋白-蛋白相互作用中起关键作用。参与细胞运动、维持细胞形状和调节转录极性。

外觀

冻干粉,含 Tris、ATP 以及 CaCl2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jarrod A Call et al.
Journal of applied physiology (Bethesda, Md. : 1985), 105(3), 923-932 (2008-06-28)
Duchenne muscular dystrophy is characterized by the absence of dystrophin from muscle cells. Dystrophic muscle cells are susceptible to oxidative stress. We tested the hypothesis that 3 wk of endurance exercise starting at age 21 days in young male mdx
Pooneh Vaziri et al.
Genetics, 216(1), 177-190 (2020-08-06)
Myosin is an essential motor protein, which in muscle is comprised of two molecules each of myosin heavy-chain (MHC), the essential or alkali myosin light-chain 1 (MLC1), and the regulatory myosin light-chain 2 (MLC2). It has been shown previously that MLC2
J A Henderson et al.
Endocrine, 33(3), 285-293 (2008-11-21)
To further understand the role of ovarian hormones in the function of the serotonin neural system, we investigated the effects of estradiol (E), progesterone (P), and raloxifene on 5HT 1A and 2C receptor protein expression in the dorsal raphe region
Robert Root-Bernstein et al.
Autoimmunity, 42(1), 1-16 (2008-07-09)
A variety of clinical, epidemiological, and experimental data suggest that rheumatic heart disease and autoimmune myocarditis are not only similar in their pathogenesis, but may often be due to combined infections with coxsackie virus (CX) and streptococcus A bacteria (SA).
Interactive sequences in the stress protein and molecular chaperone human alphaB crystallin recognize and modulate the assembly of filaments
Ghosh JG, et al.
The International Journal of Biochemistry & Cell Biology, 39(10), 1804-1815 (2007)

商品

Actin isoforms are muscle tissue markers; six isoforms expressed, four for muscle differentiation, two ubiquitous.

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