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A2754

Sigma-Aldrich

腺苷-5′-二磷酸 钠盐

bacterial, ≥95% (HPLC)

别名:

ADP钠盐, ADP

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About This Item

经验公式（希尔记法）:
C10H15N5O10P2
CAS号:
20398-34-9
分子量:
427.20
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
24890690
NACRES:
NA.51

生物源

bacterial

品質等級

300

化驗

≥95% (HPLC)

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

InChI 密鑰

XTWYTFMLZFPYCI-KQYNXXCUSA-N

基因資訊

human ... HSP90AA1(3320) , P2RY1(5028)

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相关类别

一般說明

5′-二磷酸腺苷（ADP）是一种通过 FOF1-ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP也可通过单磷酸腺苷酸（AMP）的腺苷酸激酶催化反应得到。ADP是一种血小板激动剂，由血小板致密颗粒分泌。它通过其与ADP受体P2Y1和P2Y12的相互作用影响血小板活化。ADP在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。

應用

5′-二磷酸腺苷钠盐已用作：
  • 血小板聚集的阳性对照，用聚焦仪分析纯化解聚素的抗血小板活性。
  • 制备原液以进行线粒体应激实验。
  • 流式细胞术分析中的阳性对照品，用于研究五聚体C反应蛋白（pCRP）和单体CRP（mCRP）对血小板CD62p（P-选择素）表达的影响。
  • 血小板激动剂，刺激血小板聚集。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

nwg

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000434227
0000434227
0000431808
0000431808
0000319554

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实验方案

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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